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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Array Biopharma
Curated by
ChEMBL
Ligand
BDBM50327790
((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of Akt1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Array Biopharma
Curated by
ChEMBL
Ligand
BDBM50327790
((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of AKT1 by IMAP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Array Biopharma
Curated by
ChEMBL
Ligand
BDBM50327790
((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of Akt in human LNCaP cell assessed as inhibition of PRAS40 phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proline-rich AKT1 substrate 1
(Homo sapiens (Human))
Array Biopharma
Curated by
ChEMBL
Ligand
BDBM50327790
((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of PRAS40 phosphorylation at Thr246 in human LNCaP cells after 1.5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI