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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327790((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327790((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327790((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Akt in human LNCaP cell assessed as inhibition of PRAS40 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProline-rich AKT1 substrate 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327790((R)-2-amino-3-(4-fluorophenyl)-1-(4-(5-methyl-7H-p...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PRAS40 phosphorylation at Thr246 in human LNCaP cells after 1.5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed