Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Canadian Institutes of Health Research

LigandPNGBDBM14721(2,6-di-tert-butyl-4-methyl-1-{4-[(5-sulfamoyl-1,3,...)
Affinity DataKi:  3.13nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Canadian Institutes of Health Research

LigandPNGBDBM14721(2,6-di-tert-butyl-4-methyl-1-{4-[(5-sulfamoyl-1,3,...)
Affinity DataKi:  9.40nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Canadian Institutes of Health Research

LigandPNGBDBM14721(2,6-di-tert-butyl-4-methyl-1-{4-[(5-sulfamoyl-1,3,...)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/molepH: 7.5 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Canadian Institutes of Health Research

LigandPNGBDBM14721(2,6-di-tert-butyl-4-methyl-1-{4-[(5-sulfamoyl-1,3,...)
Affinity DataKi:  34nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed