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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
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Affinity Data
EC50: 1.84E+4nM
Assay Description:
Activation of recombinant human TREK1 G275C mutant expressed in HEK293T cells assessed as increase in K+ current amplitude in presence of MTSET by wh...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
Details
Article
PubMed
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Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.28E+4nM
Assay Description:
Activation of recombinant human TREK1 expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophys...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
TREK-2 two-pore-domain K+ channel
(Mus musculus)
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
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Affinity Data
EC50: 1.13E+4nM
Assay Description:
Activation of recombinant mouse TREK2 expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophys...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.57E+3nM
Assay Description:
Activation of recombinant human TREK1 T156A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.91E+3nM
Assay Description:
Activation of recombinant human TREK1 W290A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.52E+4nM
Assay Description:
Activation of recombinant human TREK1 G275C mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 4
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.53E+4nM
Assay Description:
Activation of recombinant human TRAAK expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophys...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.24E+4nM
Assay Description:
Activation of recombinant human TREK1 F149A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium channel subfamily K member 2
(Homo sapiens (Human))
East China Normal University
Curated by
ChEMBL
Ligand
BDBM50514764
(CHEMBL4552751)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.98E+3nM
Assay Description:
Activation of recombinant human TREK1 I293A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI