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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Free fatty acid receptor 1
(Rattus norvegicus)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
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Affinity Data
Ki: 27nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from rat GPR40 receptor expressed in CHO ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
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Copy InChI
Affinity Data
Ki: 46nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from human GPR40 receptor expressed in CH...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.80nM
Assay Description:
Agonist activity against human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR assay in presence of 0.1% BS...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.70nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells by calcium flux assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 22nM
Assay Description:
Agonist activity at human GPR40 receptor expressed in CHO cells assessed as increase in intracellular calcium level for 90 secs by FLIPR assay in the...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Rattus norvegicus)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50339489
(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI