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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
21
hits in this display
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
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Affinity Data
Ki: 0.800nM
Assay Description:
Binding affinity for cloned human 5-hydroxytryptamine 1D receptor beta
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.800nM
Assay Description:
Affinity for 5-hydroxytryptamine 1B receptor subtype
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.870nM
Assay Description:
Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2nM
Assay Description:
Affinity for 5-hydroxytryptamine 1D receptor subtype
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
Assay Description:
Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
Assay Description:
Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.70nM
Assay Description:
Binding affinity towards cloned human 5-hydroxy tryptamine 1A (5-HT1A) receptor was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
Affinity for 5-hydroxytryptamine 1A receptor subtype
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
Binding affinity for cloned human 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2b
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards Alpha-2 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards 5-hydroxytryptamine 1C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards 5-hydroxy tryptamine 4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards dopaminergic (D2) receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards histaminergic (H 1) receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its affinity towards muscarinic (M) receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Serotonin 2 (5-HT2) receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determined
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 110nM
Assay Description:
Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determined
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.600nM
Assay Description:
Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50033447
(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.10nM
Assay Description:
The compound was evaluated for intrinsic activity against human cloned 5-hydroxytryptamine 1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI