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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity to integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  69nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  84nMAssay Description:Binding affinity to integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  84nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5(Homo sapiens (Human))
Shire Orphan Therapies

US Patent
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: <100nMpH: 9.6 T: 2°CAssay Description:Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-IIb(Homo sapiens (Human))
Shire Orphan Therapies

US Patent
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: >1.00E+3nMpH: 9.6 T: 2°CAssay Description:Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity to integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  2.30E+3nMAssay Description:Binding affinity to integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed