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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
P2X purinoceptor 1
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 9.40nM
Assay Description:
Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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PC sid
PDB
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Article
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Target
P2X purinoceptor 1
(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 30nM
Assay Description:
Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...
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Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
P2X purinoceptor 1
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 43nM
Assay Description:
Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulation
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
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Target
P2X purinoceptor 3
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 140nM
Assay Description:
Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
P2X purinoceptor 7
(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 600nM
Assay Description:
Antagonist activity at P2X7 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
PubMed
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Target
14-3-3 protein zeta/delta
(Homo sapiens)
Eindhoven University Of Technology
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 9.30E+3nM
Assay Description:
Binding affinity to GST-tagged 14-3-3-zeta (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS40...
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
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Article
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PDB
3D Structure (crystal)
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Target
14-3-3 protein zeta/delta
(Homo sapiens)
Eindhoven University Of Technology
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 9.30E+3nM
Assay Description:
Inhibition of PRAS40 binding to human GST-tagged 14-3-3 protein zeta/delta expressed in Escherichia coli BL21(DE3) by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
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PC sid
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
P2X purinoceptor 2
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 1.19E+4nM
Assay Description:
Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
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Article
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Target
14-3-3 protein gamma
(Homo sapiens (Human))
Eindhoven University Of Technology
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 1.64E+4nM
Assay Description:
Binding affinity to GST-tagged 14-3-3-gamma (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS4...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
P2Y purinoceptor 1
(Meleagris gallopavo)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50102295
(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of 10 nM 2-MeSADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]-inositol
More data for this Ligand-Target Pair
Target Info
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
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