Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008123(5-Cyclohexyl-2,2-difluoro-4-{3-(1H-imidazol-4-yl)-...)Copy SMILESCopy InChI

Affinity DataIC50:  0.900nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008123(5-Cyclohexyl-2,2-difluoro-4-{3-(1H-imidazol-4-yl)-...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI