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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
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Affinity Data
Ki: 700nM
Assay Description:
Displacement of [3H] dofetilide from human ERG channel expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
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Target
Cathepsin K
(Homo sapiens (Human))
Schering-Plough
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
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Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of human recombinant cathepsin K by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Schering-Plough
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of human recombinant cathepsin K using Z-Phe-Arg-MCA substrate by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Schering-Plough
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant cathepsin B by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Schering-Plough
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant cathepsin S by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Schering-Plough
Curated by
ChEMBL
Ligand
BDBM50313479
(4-cycloheptyl-6-(3-(piperidin-1-yl)propyl)pyrimidi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant cathepsin L by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI