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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cathepsin D
(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM233142
(1,2-Dipyridinylhydrazine | Mr-II-80)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of human liver cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Plasmepsin II
(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM233142
(1,2-Dipyridinylhydrazine | Mr-II-80)
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Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasmepsin II
(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM233142
(1,2-Dipyridinylhydrazine | Mr-II-80)
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Copy InChI
Affinity Data
IC50: 1.45E+3nM
pH: 5.0
Assay Description:
The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin D
(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by
ChEMBL
Ligand
BDBM233142
(1,2-Dipyridinylhydrazine | Mr-II-80)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.50E+3nM
pH: 5.0
Assay Description:
The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI