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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetArginase-2, mitochondrial(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642314((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642208((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)
Affinity DataIC50:  8nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642208((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642314((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50:  36.4nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent