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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642313
((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
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Affinity Data
IC50: 2.90nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642313
((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
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Copy InChI
Affinity Data
IC50: 3.40nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642314
((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642208
((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)
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Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642208
((5-amino-5-(1-(2-((2-fluorobenzyl)amino)- 2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.40nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
Rijksuniversiteit Groningen
US Patent
Ligand
BDBM642314
((-)-(S)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36.4nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI