Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 34 hits in this display
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: <0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: <0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: <0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: <0.0500nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
BDBM453328(BDBM553831 | US10730826, Compound 21)
IC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
BDBM453328(BDBM553831 | US10730826, Compound 21)
IC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 117nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: 170nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 170nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 380nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 380nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 380nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: 380nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 560nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 560nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: 560nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 560nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 4.68E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 4.68E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 4.68E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: 4.68E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 6.10E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 6.10E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
IC50: 2.95E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
BDBM553804(US11325884, Compound 1a-non-racemic | US11325884, ...)
IC50: 2.95E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair