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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Beta-carbonic anhydrase 1
(Mycobacterium tuberculosis)
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
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Affinity Data
Ki: 5nM
Assay Description:
Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.10nM
Assay Description:
Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.10nM
Assay Description:
Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.40nM
Assay Description:
Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.40nM
Assay Description:
Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase
(Mycobacterium tuberculosis)
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.40nM
Assay Description:
Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
In vitro inhibitory activity against human carbonic anhydrase II (hCAII)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 4
(Bos taurus (bovine))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
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Affinity Data
Ki: 21nM
Assay Description:
In vitro inhibitory activity against bovine carbonic anhydrase IV (CAIV)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 50nM
Assay Description:
Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 50nM
Assay Description:
Inhibition of human carbonic anhydrase 2 for 15 mins by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 50nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 950nM
Assay Description:
In vitro inhibitory activity against human carbonic anhydrase I (hCAI)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+3nM
Assay Description:
Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50146756
(4-(3-Pentafluorophenyl-ureido)-benzenesulfonamide ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+3nM
Assay Description:
Inhibition of human carbonic anhydrase 1 for 15 mins by stopped flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI