Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 189 hits in this display   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3nMAssay Description:Inhibition of human CA 12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition constant against human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant human transmembrane, tumor-associated form of carbonic anhydrase-12 preincubated for 15 mins by stopped flow CO2 hydration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition constant against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition constant against human (cloned) isozyme (hCA II) by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase-2 using p-nitrophenyl acetate as substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against cytosolic human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human CA2 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of full length human CA 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  15nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  23nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition constant against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition constant against human cloned isozyme (hCA IX) by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against membrane bound tumor associated human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of catalytic domain of human recombinant CA IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human CA9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 9 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human CA 9 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  24nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human CA1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human CA1 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition constant against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition constant against human (cloned) isozyme (hCA I) by the CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase-1 using p-nitrophenyl acetate as substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against cytosolic human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  47nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  47nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  65nMAssay Description:Inhibitory activity against carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
University of Tampere

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  72nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  79nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Sulfurihydrogenibium sp. (strain YO3AOP1))
Universit£

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  84nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  97nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  97nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  104nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  104nMAssay Description:Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  122nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  122nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Saccharomyces cerevisiae)
Balikesir University

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  133nMAssay Description:Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  163nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  163nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Anopheles gambiae)
University Of Tampere And Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  226nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  273nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta carbonic anhydrase(Thalassiosira weissflogii)
Universit£

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  375nMAssay Description:Inhibition of Thalassiosira weissflogii delta carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  394nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCARBONIC ANHYDRASE(Helicobacter pylori J99)
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  413nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Astrosclera willeyana)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  423nMAssay Description:Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Helicobacter pylori (strain G27))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  434nMAssay Description:Inhibition of Helicobacter pylori recombinant CAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  717nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Universite Degli Studi Di Firenze

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  963nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universite Degli Studi Di Firenze

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  1.09E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  7.84E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataIC50:  7nM EC50:  80nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataIC50:  65nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Eisai

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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