Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
59
hits in this display
Target
Adenylate kinase 2, mitochondrial
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.00E+4nM
Assay Description:
Inhibitory activity against rat adenylate kinase II was determined in the presence of ATP, non competitive inhibition
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycerol kinase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.00E+5nM
Assay Description:
Tested for its binding affinity against glycerol kinase (ATP competitive inhibition)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Adenylate kinase isoenzyme 1
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.70E+5nM
Assay Description:
Inhibitory activity against rat Adenylate kinase M isoenzyme in the presence of ATP non competitive inhibition
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
2-dehydropantoate 2-reductase
(Escherichia coli (strain K12))
University Chemical Laboratory
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.10E+5nM
Assay Description:
Inhibition of Escherichia coli KPR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of human recombinant phospho-MK2 (36-400) by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Endoplasmin
(Canis familiaris)
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.24E+3nM
Assay Description:
Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Heat shock 70 kDa protein 1A
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50192459
(ATP(4-) | adenosine 5'-triphosphate(4-) | atp | ci...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.37E+3nM
Assay Description:
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+3nM
Assay Description:
Displacement of [8-3H]ATP from human recombinant MK2 (36-400) by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Displacement of [8-3H]ATP from human recombinant MK2 (41-364) by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Heat shock cognate 71 kDa protein
(Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50192459
(ATP(4-) | adenosine 5'-triphosphate(4-) | atp | ci...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.73E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Heat shock protein 75 kDa, mitochondrial
(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.13E+4nM
Assay Description:
Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 12
(Homo sapiens (Human))
Galecto Biotech
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.51E+5nM
Assay Description:
Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 4
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 500nM
Assay Description:
Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 5
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Antagonist activity against recombinant rat P2X purinoceptor 5 (P2X5)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 2
(RAT)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.40E+3nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat receptor P2X purinoceptor 2 (P2X2) at 10 uM, expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 4
(RAT)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 6
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Antagonist activity against recombinant rat P2X purinoceptor 6 (P2X6 )
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 4
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.30E+4nM
Assay Description:
The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 6
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 1
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 56nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 4
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.80E+3nM
Assay Description:
The compound was evaluated for agonist activity against phospholipase C coupled recombinant rat P2Y purinoceptor 4 (P2Y4)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 12
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.19E+3nM
Assay Description:
Antagonist activity against phospholipase C coupled rat P2Y purinoceptor 12 (P2Y12)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 340nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 10 uM, expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
P2Y purinoceptor 4
(Rattus norvegicus)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.17E+3nM
Assay Description:
Antagonist activity at rat P2Y4
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Endoplasmin
(Canis familiaris)
Memorial Sloan-Kettering Cancer Center
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.90E+4nM
Assay Description:
Inhibition of BODIPY-AG binding to dog Grp94
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
2-dehydropantoate 2-reductase
(Escherichia coli (strain K12))
University Chemical Laboratory
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.30E+5nM
Assay Description:
Binding affinity to Escherichia coli KPR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 85nM
Assay Description:
Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Rattus norvegicus)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50422407
(CHEMBL2364735)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2nM
Assay Description:
Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.70E+3nM
Assay Description:
Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 850nM
Assay Description:
Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 95.8nM
Assay Description:
Agonist activity at N-terminal HA epitope-tagged wild type 3 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 63.1nM
Assay Description:
Agonist activity at N-terminal HA epitope-tagged wild type 4 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 4
(Mus musculus)
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 4
(RAT)
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Antagonist activity at rat P2X4 receptor by cell-based calcium influx assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 4
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincub...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.80E+3nM
Assay Description:
In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 200nM
Assay Description:
Agonist activity at P2Y2 receptor in human CF/T43 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 230nM
Assay Description:
Agonist activity at P2Y2 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 180nM
Assay Description:
Agonist activity at P2Y2 receptor in NG108-15 cells (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 200nM
Assay Description:
Agonist activity at P2Y2 receptor in BEA cells (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
(Homo sapiens (Human))
Harvard University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 69nM
Assay Description:
Binding affinity against Purine Nucleoside Phosphatase
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Yale University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.30E+3nM
Assay Description:
Binding affinity to 6XHis-tagged human JAK2 JH2 domain V617F mutant (513 to 827 residues) expressed in baculovirus infected Sf9 cells by MANT-ATP bin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Yale University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.30E+3nM
Assay Description:
Binding affinity to wild type 6XHis-tagged human JAK2 JH2 domain (513 to 827 residues) expressed in baculovirus infected Sf9 cells by MANT-ATP bindin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
CDGSH iron-sulfur domain-containing protein 1
(Homo sapiens (Human))
TBA
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.92E+3nM
Assay Description:
Binding affinity to mitoNEET (unknown origin) by ITC method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 230nM
Assay Description:
Agonist activity at human P2Y2 transfected in human 1321N1 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 4
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.20E+3nM
Assay Description:
Antagonist activity at human P2Y4
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.70E+4nM
Assay Description:
The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 230nM
Assay Description:
Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.73E+4nM
Assay Description:
Agonist activity by measuring inositol phosphate accumulation in 1321N1 human astrocytoma cells stably expressing human P2Y purinoceptor 11
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.80E+3nM
Assay Description:
Activation of Purinoceptor P2Y1-mediated phospholipase C in turkey erythrocyte membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.50E+3nM
Assay Description:
Accumulation of inositol phosphate in 1321N1 astrocytoma cells expressing human P2Y1 purinoceptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 85nM
Assay Description:
Agonist activity by measuring inositol phosphate accumulation in 1321N1 human astrocytoma cells stably expressing human P2Y purinoceptor 2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Meleagris gallopavo)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.35E+3nM
Assay Description:
Agonistic activity for P2Y purinoceptor 1 of turkey erythrocyte membranes
More data for this Ligand-Target Pair
Target Info
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 850nM
Assay Description:
Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 11
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.70E+3nM
Assay Description:
Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Meleagris gallopavo)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.80E+3nM
Assay Description:
Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytes
More data for this Ligand-Target Pair
Target Info
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 7
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.80E+5nM
Assay Description:
Antagonist activity against recombinant human P2X purinoceptor 7 (P2X7)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 850nM
Assay Description:
Agonist activity at human P2Y1 receptor expressed in human 1321N1 cells assessed as increase of intracellular calcium level after 30 mins using fura-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Rattus norvegicus)
Bar-Ilan University
Curated by
ChEMBL
Ligand
BDBM50366480
(ADENOSINE TRIPHOSPHATE | ATP)
Copy SMILES
Copy InChI
Affinity Data
EC50: 200nM
Assay Description:
Agonist activity at rat P2Y1R expressed in HEK293 cells assessed as release of intracellular calcium by fluorescence based assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Displayed 1 to 50 (of 59 total ) |
Next
|
Last
>>