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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Institute For Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
Ki: 1.10nM
pH: 9.0
Assay Description:
Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Fatty-acid amide hydrolase 1
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
Ki: 1.10nM
Assay Description:
Inhibition of FAAH
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Fatty-acid amide hydrolase 1
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
Ki: 5.5nM
Assay Description:
Inhibition of human recombinant FAAH expressed in african green monkey COS7 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Institute For Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Inhibition of rat FAAH expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
Institute For Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of rat FAAH expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Liver carboxylesterase 1
(Homo sapiens (Human))
Institute For Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of TGH
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
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Article
PubMed
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Target
Diacylglycerol lipase-alpha
(Homo sapiens (Human))
Leiden University
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human))
Institute For Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50261710
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of KIAA1363 hydrolase
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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