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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
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Affinity Data
Kd: 60nM
pH: 7.4 T: 2°C
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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antibodypedia
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KEGG
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In Depth
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Article
PubMed
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 851nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.55E+4nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 81nM
Assay Description:
Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.74E+3nM
Assay Description:
Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+5nM
Assay Description:
Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 11nM
Assay Description:
Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 661nM
Assay Description:
Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.00E+4nM
Assay Description:
Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 708nM
Assay Description:
Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25750
(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 18nM
Assay Description:
Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI