Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM92497(CHEMBL542051 | Omega-imidazolyl octanoic acid)Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:Inhibitory activity against human thromboxane synthetaseMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM92497(CHEMBL542051 | Omega-imidazolyl octanoic acid)Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:Inhibitory activity against Thromboxane synthetaseMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2E1(Homo sapiens (Human))
The University of Kansas

LigandBDBM92497(CHEMBL542051 | Omega-imidazolyl octanoic acid)Copy SMILESCopy InChI

Affinity DataKd:  2.10E+4nMAssay Description:Binding assay using CYP2E1.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI