Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetRNA demethylase ALKBH5(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of N-terminal truncated human ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human full length N-terminal His6-tagged ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH3 (1 to 286 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of full length human FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed