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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Ohio State University
Curated by
PDSP K
i
Database
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
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Affinity Data
Ki: 132nM
More data for this Ligand-Target Pair
Target Info
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Ohio State University
Curated by
PDSP K
i
Database
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 85nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
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Affinity Data
Kd: 2.04E+3nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University Of Nottingham
Curated by
ChEMBL
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
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Affinity Data
Kd: 0.331nM
Assay Description:
Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Ohio State University
Curated by
PDSP K
i
Database
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 56nM
Assay Description:
Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University Of Nottingham
Curated by
ChEMBL
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.80nM
Assay Description:
Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.91E+3nM
Assay Description:
Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Ohio State University
Curated by
PDSP K
i
Database
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 60nM
Assay Description:
Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Ohio State University
Curated by
PDSP K
i
Database
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 145nM
Assay Description:
Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University Of Nottingham
Curated by
ChEMBL
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.24nM
pH: 7.4 T: 2°C
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University Of Nottingham
Curated by
ChEMBL
Ligand
BDBM25748
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.813nM
Assay Description:
Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI