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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
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Target
Histamine H1 receptor
(Homo sapiens (Human))
Ucb Pharma
Curated by
PDSP K
i
Database
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
Ki: 1nM
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Target
Histamine H1 receptor
(Homo sapiens (Human))
Ucb Pharma
Curated by
PDSP K
i
Database
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2nM
More data for this Ligand-Target Pair
Target Info
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Target
Histamine H1 receptor
(Homo sapiens (Human))
Ucb Pharma
Curated by
PDSP K
i
Database
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Copy InChI
Affinity Data
Ki: 2nM
Assay Description:
Binding affinity to histamine H1 receptor (unknown origin)
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
Ki: 50nM
Assay Description:
Binding affinity to 5-HT2A receptor (unknown origin)
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
Ki: 300nM
Assay Description:
Displacement of [3H]prazosin from rat cerebral cortex adrenergic receptor alpha1 by liquid scintillation counting method
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
Ki: 378nM
Assay Description:
Binding affinity to D2 receptor (unknown origin)
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
Ki: >1.00E+4nM ΔG°: >-29.7kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...
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Target
Sodium channel protein type 1/2/3 subunit alpha
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...
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Target Info
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
IC50: 7.29E+4nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
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Target Info
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Target
Orf1a protein
(MERS-CoV)
University of Bonn
Ligand
BDBM22875
(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
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Affinity Data
EC50: 1.44E+4nM
Assay Description:
This is a review article.
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