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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Histone deacetylase 4
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
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Affinity Data
Ki: 8.70nM
Assay Description:
Competitive inhibition of HDAC4 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Competitive inhibition of HDAC3 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Competitive inhibition of HDAC1 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 11
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 18nM
Assay Description:
Competitive inhibition of HDAC5 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 23nM
Assay Description:
Competitive inhibition of HDAC10 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 9
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 24nM
Assay Description:
Competitive inhibition of HDAC9 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Competitive inhibition of HDAC6 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 39nM
Assay Description:
Competitive inhibition of HDAC2 using KI-104 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of full length recombinant HDAC1 using Fluor de Lys as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of recombinant HDAC1 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39nM
Assay Description:
The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39nM
Assay Description:
The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
S*Bio
Curated by
ChEMBL
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39nM
Assay Description:
The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Mei Pharma
US Patent
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 254nM
Assay Description:
To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Mei Pharma
US Patent
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 254nM
Assay Description:
The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Mei Pharma
US Patent
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 254nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone H3.1
(Homo sapiens (Human))
Mei Pharma
US Patent
Ligand
BDBM50248522
(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 500nM
Assay Description:
To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI