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Found 4 Enz. Inhib. hit(s) with Target = '[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial'
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Homo sapiens)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587492(CHEMBL5079107)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Homo sapiens)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587493(CHEMBL5087238)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Homo sapiens)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50587479(CHEMBL5082649)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Homo sapiens)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50571963(CHEMBL4855768)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant BCKDK incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed