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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab-His6'
TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandPNGBDBM581944(WO2023004291, Compound CDD-1714)
Affinity DataKi:  20nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandPNGBDBM484197(CDD-1976 | WO2023004291, Compound CDD-1976)
Affinity DataKi:  37nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandPNGBDBM484196(CDD-1713 | WO2023004291, Compound CDD-1713)
Affinity DataKi:  45nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandPNGBDBM581945(WO2023004291, Compound CDD-1886)
Affinity DataKi:  1.57E+4nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed