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Found 29 Enz. Inhib. hit(s) with Target = 'Serine protease HTRA2, mitochondrial'
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521753(US11149067, Compound Ahp13)
Affinity DataKi:  260nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521751(US11149067, Compound Ahp10)
Affinity DataKi:  260nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521744(US11149067, Compound Ahp3)
Affinity DataKi:  270nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521745(US11149067, Compound Ahp4)
Affinity DataKi:  490nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521755(US11149067, Compound Ahp15)
Affinity DataKi:  690nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521754(US11149067, Compound Ahp14)
Affinity DataKi:  700nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521759(US11149067, Compound Ahp19)
Affinity DataKi:  1.11E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521757(US11149067, Compound Ahp17)
Affinity DataKi:  1.38E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521747(US11149067, Compound Ahp6)
Affinity DataKi:  2.10E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521749(US11149067, Compound Ahp8)
Affinity DataKi:  2.30E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521750(US11149067, Compound Ahp9)
Affinity DataKi:  2.80E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521752(US11149067, Compound Ahp11)
Affinity DataKi:  4.00E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521742(US11149067, Compound Ahp1)
Affinity DataKi:  4.10E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi:  6.90E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521756(US11149067, Compound Ahp16)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521746(US11149067, Compound Ahp5)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521743(US11149067, Compound Ahp2)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521761(US11149067, Compound Ahp21)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521760(US11149067, Compound Ahp20)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614602(CHEMBL5277138)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614603(CHEMBL5286341)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614600(CHEMBL5274566)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614601(CHEMBL5284442)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614605(CHEMBL5278663)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614606(CHEMBL5275102)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614608(CHEMBL2430327)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614607(CHEMBL5283566)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50614604(CHEMBL5280693)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
In DepthDetails PubMed