Query String: Genistein
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one BDBM19459 US8552057, 2 Genistein Genistein, 8 CHEMBL44 cid_5280961 Genisteol Prunetol
- Wang, Y; Ma, L; Pang, C; Huang, M; Huang, Z; Gu, L Synergetic inhibition of genistein and D-glucose on alpha-glucosidase. Bioorg Med Chem Lett 14: 2947-50 (2004)
- Qiang, X; Sang, Z; Yuan, W; Li, Y; Liu, Q; Bai, P; Shi, Y; Ang, W; Tan, Z; Deng, Y Design, synthesis and evaluation of genistein-O-alkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease. Eur J Med Chem 76: 314-31 (2014)
- Stevens, MF; McCall, CJ; Lelieveld, P; Alexander, P; Richter, A; Davies, DE Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin. J Med Chem 37: 1689-95 (1994)
- ChEMBL_34554 (CHEMBL646887) Inhibition of yeast alpha-glucosidase by genistein
- ChEMBL_34557 (CHEMBL872366) Inhibition kinetics of yeast alpha-glucosidase by genistein at a concentration of 10.2 uM
- ChEMBL_834525 (CHEMBL2073574) Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells stimulated forskolin and potentiator genistein with assessed as iodide influx incubated for 24 hrs
- ChEMBL_1437226 (CHEMBL3383566) Activity of human CFTR F508 deletion mutant expressed in FRT cells assessed as potentiation of genistein-induced iodine ion influx after 24 hrs by YFP-H148Q/I152L fluorescent quenching assay
- ChEMBL_1730605 (CHEMBL4146141) Corrector activity at human CFTR F508-del mutant expressed in rat FTR cells harboring YFP-H148Q/I152L preincubated for 18 to 24 hrs followed by forskolin/genistein addition by HTS assay
- ChEMBL_1730608 (CHEMBL4146144) Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by forskolin/genistein stimulation for 30 mins by fluorescence assay
- ChEMBL_2056164 (CHEMBL4711165) Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forskolin and genistein addition for 30 mins by fluorescence based assay
- ChEMBL_813056 (CHEMBL2020568) Activity at human CFTR delta F508 mutant expressed in forskolin-stimulated FRT cells assessed as increase in iodine influx measured as decrease in YFP fluorescence after 18 to 24 hrs at 37 degC in presence of genistein
- ChEMBL_1867091 (CHEMBL4368066) Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as iodide influx preincubated for 18 to 24 hrs followed by compound wash out and addition of forskolin and genistein by fluorescence based assay
- ChEMBL_1867095 (CHEMBL4368070) Corrector activity at human CFTR F508del mutant expressed in rat FRT cells iodide influx incubated for 16 to 20 hrs followed by compound wash out and addition of forskolin and genistein and measured after 20 mins by fluorescence based assay
- ChEMBL_2486692 Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing halide-sensitive yellow fluorescent protein assessed as increase in iodide influx preincubated with compound for 24 hrs followed by compound washout and measured after 30 mins of stimulation with forskolin/genistein by fluorescence microplate reader
- ChEMBL_2486693 Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing halide-sensitive yellow fluorescent protein assessed as increase in iodide influx preincubated with compound for 24 hrs in presence of VX-809 followed by compound washout and measured after 30 mins of stimulation with forskolin/genistein by fluorescence microplate reader