Query String: calcium
- calcium release-activated calcium channel protein 1
- calcium channel
- calcium channel (ver)
- calcium pump 1
- calcium pump 3
- calcium regulator sv2a
- calcium sensing receptor
- calcium release-activated calcium channel protein/stromal interaction molecule 1
- brain calcium channel ii
- calcium channel (type l)
- calcium dependent protein kinase
- calcium-activated neutral proteinase
- calcium-independent phospholipase a2
- l-type calcium channel
- voltage-gated calcium channel
- calcium-dependent protease small subunit
- calcium-dependent protein kinase 1
- calcium-dependent protein kinase 2
- calcium-dependent protein kinase 4
- parathyroid cell calcium-sensing receptor
- voltage-dependent l-type calcium channel subunit beta-1/n-type calcium channel subunit alpha-1b/calcium channel subunit alpha-2/delta-1
- calcium-activated potassium channel subunit beta
- calcium-dependent protein kinase 1 (cdpk1)
- small conductance calcium-activated potassium channel
- voltage-dependent calcium channel alpha2delta subunit
- voltage-gated l-type calcium channel
- voltage-gated t-type calcium channel
- calcium/calmodulin-dependent protein kinase kinase 2
- cav1.2/β3/α2δ-1 calcium channel
- t-type calcium channel alpha 1g subunit
- voltage-dependent calcium channel alpha-1 subunit
- voltage-dependent calcium channel gamma-1 subunit
- calcium/calmodulin-dependent protein kinase kinase 2 (camkkb)
- calcium/calmodulin-dependent protein kinase kinase 2 [ p274e]
- ef-hand calcium-binding domain-containing protein 4b
- l-type calcium channel alpha 1c/beta 2a
- low-voltage-activated calcium channel alpha1 3.2 subunit
- small conductance calcium-activated potassium channel protein 1
- small conductance calcium-activated potassium channel protein 2
- small conductance calcium-activated potassium channel protein 3
- calcium channel, voltage-dependent, n type, alpha 1b subunit
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1b
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1c
- calcium/calmodulin-dependent protein kinase type ii beta chain
- calcium/calmodulin-dependent protein kinase type ii subunit alpha
- calcium/calmodulin-dependent protein kinase type iv [15-340]
- small conductance calcium-activated potassium channel protein 1 (kca2.1)
- small conductance calcium-activated potassium channel protein 2 (kca2.2)
- voltage-dependent calcium channel subunit alpha-2/delta-1
- voltage-dependent l-type calcium channel alpha1c/alpha2delta/beta1b
- voltage-dependent l-type calcium channel subunit alpha-1c
- voltage-dependent n-type calcium channel subunit alpha-1b
- voltage-dependent t-type calcium channel subunit alpha-1g
- voltage-dependent t-type calcium channel subunit alpha-1h
- voltage-gated calcium channel subunit alpha-2/delta-1
- voltage-gated l-type calcium channel alpha-1c subunit
- voltage-gated l-type calcium channel alpha-1d subunit
- voltage-gated l-type calcium channel alpha-1s subunit
- voltage-gated t-type calcium channel alpha-1i subunit
- calcium release-activated calcium channel protein 1/short transient receptor potential channel 1/short transient receptor potential channel 3/stromal interaction molecule 1
- dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1c/dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1b/phosphodiesterase
- calcium/calmodulin-dependent protein kinase type ii subunit gamma (camkllg)
- l-type calcium channel alpha-1c/beta-2/alpha2delta-1
- n-type calcium channel alpha-1b/alpha2delta-1/beta-1b
- calcium channel, l type, alpha-1 polypeptide, isoform 1, cardiac muscle
- calcium-transporting atpase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform
- dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a
- calcium/calmodulin-dependent protein kinase type ii subunit alpha/beta/delta/gamma
- dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a (pde1a1)
- dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a/1b
- voltage-dependent calcium channel subunit alpha-2/delta-1 (aa 25-1103)
- dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a/1b/1c
- large conductance calcium-activated potassium channel subfamily m alpha member 1 isoform b
- voltage-dependent l-type calcium channel subunit alpha-1c/alpha-1d/alpha-1s
- n-type calcium channel subunits alpha 1b (cav2.2), beta 3, and alpha 2 delta
- calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like ef hands
- calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like ef hands
- voltage-dependent l-type calcium channel subunit alpha-1c/alpha-1d/alpha-1f/alpha-1s
- voltage-dependent l-type calcium channel subunit beta-1/alpha-1b/alpha-2/delta-1
Calcium Folinate Folinic Acid Leucovorin calcium preservative free Wellcovorin Folinate-Sf Calcium Calc Folinate BDBM50247893 Leucovorin Calcium Citrovorum Factor Fusilev Folacal
calcium Ca2+ BDBM14
Atorvastatin Calcium Atorvastatin BDBM50442868
PITAVASTATIN CALCIUM Livalo cid_24848419 BDBM50371229
ROSUVASTATIN CALCIUM US9006282, Rosuvastatin Crestor Rosuvastatin BDBM50371228
Fenoprofen calcium;2-(3-phenoxyphenyl)propionic acid;hydrate cid_16219353 calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate UNM-0000306101 BDBM54705 CHEMBL1297
Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2) CHEMBL393220 US9006282, Atorvastatin calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate} BDBM50221993 atorvastatin calcium
Folinic Acid (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid 5-CHO-H4PteGlu1 LEVOLEUCOVORIN CALCIUM LEUCOVORIN CALCIUM Levoleucovorin BDBM286 Leucovorin
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- Calcium Mobilization Assay Calcium mobilization assay using MCHR1.
- Calcium Mobilization Assay Calcium mobilization assay using Bradykinin-1 receptor.
- Calcium Fluorescence Assay (FLIPR) CXCR2 inhibition using calcium fluorescence assay (FLIPR).
- ChEMBL_333793 (CHEMBL864733) Inhibitory activity against N-type calcium channel by calcium influx into IMR32 cells
- Calcium Uptake Assay Calcium uptake assay: The inhibition of TRPV3 receptor activation was followed as inhibition of 2-aminoethoxydiphenylborate (2-APB) induced cellular uptake of radioactive calcium.
- ChEBML_42910 Reduction in amplitude of calcium-dependent slow-response action potential by blocking voltage sensitive calcium channel
- ChEMBL_326644 (CHEMBL863377) Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR
- ChEMBL_482230 (CHEMBL960265) Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilization
- ChEMBL_652584 (CHEMBL1225787) Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium
- ChEMBL_652596 (CHEMBL1225799) Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium
- ChEMBL_748606 (CHEMBL1780459) Inhibition of Cav1.2 calcium channel
- ChEMBL_1467725 (CHEMBL3411162) Induction of calcium release in human FPR2 receptor-expressed HEK cell by cytosolic-free calcium assay
- ChEMBL_1467726 (CHEMBL3411163) Induction of calcium release in mouse FPR2 receptor-expressed HEK cell by cytosolic-free calcium assay
- ChEMBL_326645 (CHEMBL870549) Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptor
- ChEMBL_1617108 (CHEMBL3859177) Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay
- ChEMBL_2440244 Antagonist activity at human TRPC3 stably expressed in HEK293 cells inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_2440245 Antagonist activity at mouse TRPC4 stably expressed in HEK293 cells inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_2440246 Antagonist activity at human TRPC5 stably expressed in HEK293 cells inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_2440247 Antagonist activity at mouse TRPC6 stably expressed in HEK293 cells inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_2440248 Antagonist activity at human TRPC7 stably expressed in HEK293 cells inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_478755 (CHEMBL923632) Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
- ChEMBL_478758 (CHEMBL936489) Activity at SER4 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
- ChEMBL_157219 (CHEMBL769543) Inhibition of calcium-independent Phosphodiesterase 4
- ChEMBL_714878 (CHEMBL1663824) Inhibition of rat SK Calcium channel
- ChEMBL_819963 (CHEMBL2032550) Inhibition of CCR2-mediated calcium mobilization
- ChEMBL_2479555 Antagonist activity at human TRPC5 expressed in HEK293 cells assessed as inhibition of calcium influx by calcium fluorescence assay
- ChEMBL_580004 (CHEMBL1051692) Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assay
- ChEMBL_580005 (CHEMBL1051693) Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assay
- ChEBML_1553171 Inhibition of mitochondrial sodium/calcium exchanger (unknown origin)
- ChEBML_184418 Binding affinity against rat L-type calcium channel
- ChEMBL_217680 (CHEMBL819974) Inhibitory constant against calcium channel receptors (CCRs)
- ChEMBL_2268550 Binding affinity to calcium channel alpha2delta1 (unknown origin)
- ChEMBL_2579072 Inhibition of L-type calcium channel (unknown origin)
- ChEMBL_306770 (CHEMBL831867) Inhibition of calcium mobilization in human eosinophils
- ChEMBL_698200 (CHEMBL1646505) Inhibition of T-type alpha1G calcium channel
- ChEMBL_2074152 (CHEMBL4729686) Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assay
- ChEMBL_425704 (CHEMBL913686) Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assay
- ChEMBL_425706 (CHEMBL913688) Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assay
- ChEMBL_580001 (CHEMBL1051689) Agonist activity at FPR1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assay
- ChEMBL_580002 (CHEMBL1051690) Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assay
- ChEMBL_580003 (CHEMBL1051691) Agonist activity at FPRL2 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assay
- ChEMBL_946149 (CHEMBL2343551) Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysis
- ChEBML_1569846 Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mobilization assay
- ChEBML_1569848 Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mobilization assay
- ChEMBL_2074151 (CHEMBL4729685) Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assay
- ChEMBL_312816 (CHEMBL824893) Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay
- ChEMBL_312836 (CHEMBL837923) Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay
- ChEMBL_312849 (CHEMBL874928) Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay
- ChEMBL_312894 (CHEMBL827414) In vitro antagonism of N-type calcium channels expressed in PC12 cells was determined as the increase in intracellular calcium influx
- ChEMBL_744268 (CHEMBL1772075) Antagonist activity at rat mGluR5 expressed in HEK293T cells assessed as inhibition of glutamate-induced calcium flux by calcium fluorescence assay
- ChEMBL_744269 (CHEMBL1772076) Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assay
- ChEMBL_946147 (CHEMBL2343549) Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysis
- ChEBML_164619 Blockade of calcium-evoked contractions in depolarized aortic strips
- ChEMBL_1503813 (CHEMBL3592797) Inhibition of L-type calcium channel (unknown origin)
- ChEMBL_1538962 (CHEMBL3737861) Inhibition of voltage-gated calcium channel (unknown origin)
- ChEMBL_1831791 (CHEMBL4331799) Inhibition of T-type calcium channel (unknown origin)
- ChEMBL_1831792 (CHEMBL4331800) Inhibition of L-type calcium channel (unknown origin)
- ChEMBL_184418 (CHEMBL791520) Binding affinity against rat L-type calcium channel
- ChEMBL_2051986 (CHEMBL4706987) Inhibition of human L-type calcium channel Cav1.2
- ChEMBL_305449 (CHEMBL830124) Inhibitory activity against sarco- endoplasmic reticulum calcium-ATPase
- ChEMBL_384999 (CHEMBL869824) Inhibition of 5HT2C assessed as intracellular calcium concentration
- ChEMBL_42936 (CHEMBL654578) Displacement of [3H]nitrendipine from calcium channel receptor
- ChEMBL_42938 (CHEMBL654580) Displacement of [3H]nitrendipine from calcium channel receptor
- ChEMBL_42946 (CHEMBL884266) Inhibition of cAMP-specific calcium-independent phosphodiesterase (IPDE)
- ChEMBL_42947 (CHEMBL656312) Inhibition of cAMP-specific calcium-independent phosphodiesterase (IPDE).
- ChEMBL_43095 (CHEMBL658419) Inhibition of Calcium/calmodulin-dependent protein kinase II
- ChEMBL_441127 (CHEMBL891341) Inhibition of calcium channel Cav2.2 in IMR32 cells
- ChEMBL_578447 (CHEMBL1060568) Antagonist activity against T-type calcium channel alpha1G
- ChEMBL_629700 (CHEMBL1121060) Inhibition of N-type calcium channel Alpha-1B
- ChEMBL_698198 (CHEMBL1646503) Binding affinity to T-type alpha1G calcium channel
- ChEMBL_698199 (CHEMBL1646504) Binding affinity to T-type alpha1I calcium channel
- ChEMBL_789640 (CHEMBL1924725) Antagonist activity at CCR2 by calcium mobilization assay
- ChEMBL_1569846 (CHEMBL3788051) Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mobilization assay
- ChEMBL_1569848 (CHEMBL3788053) Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mobilization assay
- ChEMBL_1764848 (CHEMBL4200095) Agonist activity at rat GPR17 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by calcium 5-dye based assay
- ChEMBL_1764849 (CHEMBL4200096) Agonist activity at mouse GPR17 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by calcium 5-dye based assay
- ChEMBL_1846730 (CHEMBL4347271) Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by calcium-3 dye based FLIPR analysis
- ChEMBL_1846750 (CHEMBL4347291) Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Calcium-5 dye based fluorescence assay
- ChEMBL_2211902 (CHEMBL5124851) Agonist activity at human A1 receptor expressed in Flp-In-CHO cells assessed as stimulation of calcium mobilization by calcium mobilization assay
- ChEMBL_449860 (CHEMBL898964) Inhibition of T-type calcium channel Cav3.1 alpha-1G subunit expressed in HEK293 cells assessed as calcium current by patch-clamp assay
- ChEMBL_591452 (CHEMBL1055304) Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assay
- ChEMBL_610755 (CHEMBL1064390) Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by FLIPR assay
- Calicum Fluorescence Assay The assay is based on the detection of intracellular calcium changes detected by the selective, calcium-chelating dye, Fluo-4 (Molecular Probes).
- ChEMBL_1741070 (CHEMBL4156820) Agonist activity at CXCR4 in human CCRF-CEM cells assessed as induction of calcium release incubated for 25 mins by calcium flux assay
- ChEMBL_1891599 (CHEMBL4393426) Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calcium 4 assay
- ChEMBL_2015644 (CHEMBL4669222) Inhibition of human V1a receptor expressed in human 1321N1 cells assessed as decrease in Arg8-vasopressin-stimulated calcium flux by fluorometric calcium assay
- ChEMBL_2222608 (CHEMBL5135942) Agonist activity at human 5-HT2A receptor expressed in cells assessed as increase in calcium mobilization by Calcium-6 dye based FLIPR assay
- ChEMBL_2250308 (CHEMBL5164518) Antagonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calcium mobilization assay
- ChEMBL_2250309 (CHEMBL5164519) Antagonist activity at human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calcium mobilization assay
- ChEMBL_2250310 (CHEMBL5164520) Antagonist activity at human muscarinic M3 receptor expressed in CHO cells co-expressing Gqi5 assessed as intracellular calcium mobilization by calcium mobilization assay
- ChEMBL_312914 (CHEMBL826596) Inhibition of 50% of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay
- ChEMBL_462215 (CHEMBL945984) Antagonist activity at mu opioid receptor expressed in CHO cells assessed as release of intracellular calcium ions by aequorin luminescence-based calcium assay
- ChEMBL_462216 (CHEMBL945985) Antagonist activity at delta opioid receptor expressed in CHO cells assessed as release of intracellular calcium ions by aequorin luminescence-based calcium assay
- ChEMBL_629724 (CHEMBL1121084) Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay
- ChEMBL_629725 (CHEMBL1121085) Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay
- ChEBML_1625981 Agonist activity at GPR40 (unknown origin) by calcium flux assay
- ChEBML_1719237 Inhibition of 5-HT2B (unknown origin) by calcium flux assay
- ChEMBL_1719145 (CHEMBL4134145) Agonist activity at mouse GPR120 by calcium flux assay
- ChEMBL_1719146 (CHEMBL4134146) Agonist activity at human GPR40 by calcium flux assay
- ChEMBL_1741071 (CHEMBL4156821) Antagonist activity at L-type calcium channel (unknown origin)
- ChEMBL_1743511 (CHEMBL4178021) Inhibition of Cryptosporidium parvum calcium-dependent protein kinase 2
- ChEMBL_197571 (CHEMBL804023) Inhibition of hSK1 calcium activated potassium channel (SKCa channel)
- ChEMBL_217678 (CHEMBL819972) Displacement of [3H]nitrendipine from calcium channel receptors (CCRs)
- ChEMBL_2220239 (CHEMBL5133573) Binding affinity to OX1R (unknown origin) by calcium assay
- ChEMBL_2350515 Antagonist activity at human P2X7 receptor by calcium flux assay
- ChEMBL_2350516 Antagonist activity at rat P2X7 receptor by calcium flux assay
- ChEMBL_2350517 Antagonist activity at mouse P2X7 receptor by calcium flux assay
- ChEMBL_2460917 Antagonist activity at rat P2X7 receptor by calcium flux assay
- ChEMBL_43103 (CHEMBL657560) Inhibition of Calcium/calmodulin-dependent protein kinase type II
- ChEMBL_43104 (CHEMBL657561) Inhibition of Calcium/calmodulin-dependent protein kinase type II
- ChEMBL_43111 (CHEMBL653818) Inhibition of Calcium/calmodulin-dependent protein kinase type II
- ChEMBL_487962 (CHEMBL1013093) Activity at mGluR4 assessed as calcium mobilization by FLIPR
- ChEMBL_497239 (CHEMBL1006192) Binding affinity to RYR1 channels by calcium mobilization assay
- ChEMBL_538845 (CHEMBL1033088) Inhibition of T-type calcium channel alpha1I by FLIPR
- ChEMBL_560248 (CHEMBL1019587) Inhibition of human ERG by calcium-flux based assay
- ChEMBL_700439 (CHEMBL1647978) Blockade of Cav2.2 channel by fluorescent calcium-influx assay
- ChEMBL_754894 (CHEMBL1805878) Binding affinity at voltage-gated calcium channel subunit alpha2delta1
- ChEMBL_754900 (CHEMBL1805884) Binding affinity at voltage-gated calcium channel subunit alpha2delta2
- ChEMBL_797551 (CHEMBL1943467) Inhibition of T-type calcium channel alpha 1 G
- ChEMBL_797552 (CHEMBL1943468) Inhibition of N-type calcium channel alpha 1 B
- ChEMBL_805767 (CHEMBL1958510) Antagonist activity at rat TRPM8 by calcium flux assay
- ChEMBL_805768 (CHEMBL1958511) Antagonist activity at human TRPM8 by calcium flux assay
- ChEMBL_92767 (CHEMBL700067) Binding affinity against L-type calcium channel verapamil site
- ChEMBL_92939 (CHEMBL700953) Binding affinity against L-type calcium channel verapamil site
- ChEBML_1613522 Inhibition of T-type calcium channel Cav3.3 (unknown origin) expressed in HEK293 cells assessed as calcium influx by Fluo-4-AM dye-based FLIPR assay
- ChEMBL_1460274 (CHEMBL3370190) Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by FLIPR calcium assay
- ChEMBL_1890515 (CHEMBL4392269) Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as induction of calcium mobilization by calcium-4 dye based FLIPR assay
- ChEMBL_2071783 (CHEMBL4727317) Antagonist activity at human V1a receptor expressed in human 1321N1 cells assessed as decrease in Arg8-vasopressin-stimulated calcium flux by fluorometric calcium assay
- ChEMBL_2192630 (CHEMBL5104990) Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging assay
- ChEMBL_2236118 (CHEMBL5149890) Agonist activity at human 5-HT2A receptor assessed as activation of calcium mobilization incubated for 2 mins by Calcium-6 dye based FLIPR assay
- ChEMBL_2473595 Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx preincubated 300 secs followed by addition of KCL/CaCl2 and measured for 300 secs in presence of Cav1 blocker nifedipine by calcium 6 dye based calcium influx assay
- ChEBML_1658036 Inhibition of Syk in human Ramos B cells assessed as decrease in intracellular calcium flux measured for 3.5 mins by calcium-5 dye based FLIPR assay
- ChEMBL_1613531 (CHEMBL3855331) Inhibition of T-type calcium channel Cav3.1 (unknown origin) expressed in HEK293 cells assessed as calcium influx by Fluo-4-AM dye-based FLIPR assay
- ChEMBL_1767816 (CHEMBL4219928) Positive allosteric modulation of human GlyRalpha1 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_1767817 (CHEMBL4219929) Positive allosteric modulation of human GlyRalpha1beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_1767818 (CHEMBL4219930) Positive allosteric modulation of human GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_1767819 (CHEMBL4219931) Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_1767820 (CHEMBL4219932) Positive allosteric modulation of mouse GlyRalpha1 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_1767821 (CHEMBL4219933) Positive allosteric modulation of mouse GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay
- ChEMBL_435298 (CHEMBL903656) Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp method
- ChEBML_1686345 Antagonist activity at human TRPA1 by calcium flux based FLIPR assay
- ChEBML_88346 Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophils
- ChEMBL_1352456 (CHEMBL3270977) Inhibition of BTK-induced calcium flux in human Ramos cells
- ChEMBL_1525064 (CHEMBL3635102) Positive allosteric modulation of human mGluR1 by calcium mobilization assay
- ChEMBL_1525066 (CHEMBL3635104) Positive allosteric modulation of human mGluR4 by calcium mobilization assay
- ChEMBL_1618437 (CHEMBL3860606) Agonist activity mouse FFA4 by Gq-dependent calcium mobilization assay
- ChEMBL_1625981 (CHEMBL3868450) Agonist activity at GPR40 (unknown origin) by calcium flux assay
- ChEMBL_1668372 (CHEMBL4018260) Antagonist activity at rat M4 receptor by calcium mobilization assay
- ChEMBL_2023210 (CHEMBL4677023) Agonist activity at TRPA1 (unknown origin) by calcium imaging assay
- ChEMBL_2034076 (CHEMBL4688234) Positive allosteric modulation of human mGluR4 by calcium mobilization assay
- ChEMBL_2034080 (CHEMBL4688238) Negative allosteric modulation of human mGluR1 by calcium mobilization assay
- ChEMBL_2081556 (CHEMBL4737347) Agonist activity at FPR2 (unknown origin) by calcium mobilization assay
- ChEMBL_2149182 (CHEMBL5033580) Antagonist activity against CXCR2 (unknown origin) by calcium flux assay
- ChEMBL_217676 (CHEMBL819970) Displacement of diltiazem from L-type calcium channel binding site
- ChEMBL_217677 (CHEMBL819971) Displacement of verapamil from L-type calcium channel binding site
- ChEMBL_223712 (CHEMBL845815) Displacement of DHP from L-type calcium channel binding site
- ChEMBL_223715 (CHEMBL845818) Displacement of diltiazem from L-type calcium channel binding site
- ChEMBL_223716 (CHEMBL844976) Displacement of verapamil from L-type calcium channel binding site
- ChEMBL_2298072 Positive allosteric modulation of human GPR40 by calcium based FLIPR analysis
- ChEMBL_306304 (CHEMBL828596) Inhibition of Human gonadotropin-releasing hormone receptor stimulated calcium flux
- ChEMBL_344574 (CHEMBL868440) Inhibition of human B1 receptor by calcium influx functional assay
- ChEMBL_361273 (CHEMBL853310) Binding affinity to verapamil site of N type calcium channel
- ChEMBL_376306 (CHEMBL867962) Activity at human FPRL1-mediated calcium mobilization in CHO cells
- ChEMBL_455781 (CHEMBL887787) Antagonist activity at NMDA NR2B receptor assessed as calcium flux
- ChEMBL_487433 (CHEMBL1020888) Activity at 5HT1B receptor assessed as calcium mobilization by FLIPR
- ChEMBL_487435 (CHEMBL1020890) Activity at 5HT1D receptor assessed as calcium mobilization by FLIPR
- ChEMBL_487437 (CHEMBL1020892) Activity at 5HT2A receptor assessed as calcium mobilization by FLIPR
- ChEMBL_487439 (CHEMBL1020894) Activity at 5HT2B receptor assessed as calcium mobilization by FLIPR
- ChEMBL_487441 (CHEMBL1020896) Activity at 5HT6 receptor assessed as calcium mobilization by FLIPR
- ChEMBL_487443 (CHEMBL1020898) Activity at 5HT7 receptor assessed as calcium mobilization by FLIPR
- ChEMBL_555927 (CHEMBL956663) Binding affinity at human GnRH receptor by calcium mobilization assay
- ChEMBL_566267 (CHEMBL953570) Antagonist activity at human 5HT3 receptor by calcium influx assay
- ChEMBL_727146 (CHEMBL1687117) Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilization
- ChEMBL_748931 (CHEMBL1781379) Antagonist activity at human P2X7 receptor by calcium flux assay
- ChEMBL_748932 (CHEMBL1781380) Antagonist activity at rat P2X7 receptor by calcium flux assay
- ChEMBL_772771 (CHEMBL1837510) Inhibition of rabbit B1 receptor by cellular calcium flux assay
- ChEMBL_776885 (CHEMBL1914019) Antagonist activity at OX1R intracellular calcium mobilization by FLIPR assay
- ChEMBL_859279 (CHEMBL2166567) Agonist activity at GPR120 assessed as stimulation of calcium mobilization
- ChEMBL_982508 (CHEMBL2427816) Agonist activity at GPR30 (unknown origin) by calcium mobilization assay
- ChEMBL_1658036 (CHEMBL4007648) Inhibition of Syk in human Ramos B cells assessed as decrease in intracellular calcium flux measured for 3.5 mins by calcium-5 dye based FLIPR assay
- ChEMBL_1766323 (CHEMBL4201570) Agonist activity at recombinant human OTR expressed in CHO-DUKX-A2 cells assessed as stimulation of intracellular calcium concentration by calcium 3 dye based FLIPR assay
- ChEMBL_2275451 Agonist activity at human FPR1 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay
- ChEMBL_2275452 Agonist activity at human FPR2 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay
- ChEMBL_523080 (CHEMBL1004110) Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as glutamate-induced calcium flux preincubated for 140 sec before glutamate challenge by calcium fluorescence assay
- ChEBML_1683148 Antagonist activity at human recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by calcium-4 staining based FLIPR assay
- ChEBML_1683149 Antagonist activity at rat recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by calcium-4 staining based FLIPR assay
- ChEMBL_1474583 (CHEMBL3423872) Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagent-based fluorescence assay
- ChEMBL_1474584 (CHEMBL3423873) Antagonist activity at human mGluR5 expressed in human embryonic kidney cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagent-based fluorescence assay
- ChEMBL_1795473 (CHEMBL4267590) Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium flux measured for 120 secs by calcium-5 dye based assay
- ChEMBL_1832214 (CHEMBL4332222) Antagonist activity at mouse CCR1 assessed as inhibition of MIP-1 alpha-induced calcium flux by Fluo-4 NW or Calcium 4 dye based FLIPR TETRA assay
- ChEMBL_1891594 (CHEMBL4393421) Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux under UV-light irradiation by Calcium 4 assay
- ChEMBL_1987910 (CHEMBL4621457) Antagonist activity at human Gq-coupled 5HT2B receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium mobilization by calcium-sensitive dye based FLIPR assay
- ChEMBL_2147043 (CHEMBL5031389) Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assay
- ChEMBL_2147045 (CHEMBL5031391) Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assay
- ChEMBL_2365557 Activation of SERCA2a in mouse HL-1 cells assessed as increase in caffeine-induced calcium release incubated for 2 hrs by FLIPR Calcium 6 dye based caffeine assay
- ChEBML_141327 Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cells
- ChEBML_141328 Inhibition of N-type calcium channel in IMR-32 human neuroblastoma cells
- ChEBML_141440 In vitro inhibition of N-type calcium channels in IMR-32 cells.
- ChEBML_42759 Inhibition of [3H]nitrendipine binding to calcium channels of guinea pig myocardium
- ChEBML_42776 Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.
- ChEBML_42944 Inhibition of Calcium-dependent protein kinase 1 (CDPK-1) from maize seedlings
- ChEBML_88713 In vitro inhibition against N-type calcium influx in IMR-32 cells
- ChEMBL_141329 (CHEMBL752908) Inhibition of N-type calcium channels in IMR32 human neuroblastoma cells
- ChEMBL_141330 (CHEMBL752909) Inhibition of N-type calcium channels in IMR32 human neuroblastoma cells
- ChEMBL_1686345 (CHEMBL4036824) Antagonist activity at human TRPA1 by calcium flux based FLIPR assay
- ChEMBL_1704880 (CHEMBL4056113) Antagonist activity at rat muscarinic M5 receptor by calcium mobilization assay
- ChEMBL_1704883 (CHEMBL4056116) Antagonist activity at rat muscarinic M4 receptor by calcium mobilization assay
- ChEMBL_1704884 (CHEMBL4056117) Antagonist activity at rat muscarinic M3 receptor by calcium mobilization assay
- ChEMBL_1704885 (CHEMBL4056118) Antagonist activity at rat muscarinic M2 receptor by calcium mobilization assay
- ChEMBL_1704888 (CHEMBL4056121) Antagonist activity at rat muscarinic M1 receptor by calcium mobilization assay
- ChEMBL_2034073 (CHEMBL4688231) Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assay
- ChEMBL_2034082 (CHEMBL4688240) Positive allosteric modulation of mGluR8 (unknown origin) by calcium mobilization assay
- ChEMBL_2034084 (CHEMBL4688242) Positive allosteric modulation of mGluR2 (unknown origin) by calcium mobilization assay
- ChEMBL_2034085 (CHEMBL4688243) Positive allosteric modulation of mGluR3 (unknown origin) by calcium mobilization assay
- ChEMBL_2034086 (CHEMBL4688244) Positive allosteric modulation of mGluR6 (unknown origin) by calcium mobilization assay
- ChEMBL_217681 (CHEMBL819975) Inhibitory constant against calcium channel receptors (CCRs) from rat cortex homogenate
- ChEMBL_2220461 (CHEMBL5133795) Antagonist activity at OX1R (unknown origin) by cell-based calcium assay
- ChEMBL_2220462 (CHEMBL5133796) Antagonist activity at OX2R (unknown origin) by cell-based calcium assay
- ChEMBL_2275433 Agonist activity at FPR2 (unknown origin) assessed as increase in calcium flux
- ChEMBL_2292812 Antagonist activity at TRPM8 (unknown origin) assessed as reduction in calcium influx
- ChEMBL_2308069 Inhibition of voltage dependent L-type calcium channel in rat A7R5 cells
- ChEMBL_2313311 Agonist activity at EP4 (unknown origin) assessed as increase in calcium flux
- ChEMBL_2315011 Agonist activity at 5-HT1A receptor (unknown origin) by calcium flux assay
- ChEMBL_2315012 Antagonist activity at 5-HT1A receptor (unknown origin) by calcium flux assay
- ChEMBL_2315015 Agonist activity at 5-HT2A receptor (unknown origin) by calcium flux assay
- ChEMBL_2315016 Antagonist activity at 5-HT2A receptor (unknown origin) by calcium flux assay
- ChEMBL_2315019 Agonist activity at 5-HT2B receptor (unknown origin) by calcium flux assay
- ChEMBL_2315020 Antagonist activity at 5-HT2B receptor (unknown origin) by calcium flux assay
- ChEMBL_305795 (CHEMBL827983) Inhibitory concentration against human calcium receptor expressed in HEK 293 cells
- ChEMBL_312509 (CHEMBL833257) Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay
- ChEMBL_329115 (CHEMBL863431) Calcium mobilization mediated by CCR4 receptor in CEMS529 cells by FLIPR
- ChEMBL_335664 (CHEMBL860564) Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPR
- ChEMBL_348518 (CHEMBL865700) Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPR
- ChEMBL_421070 (CHEMBL854907) Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cells
- ChEMBL_42913 (CHEMBL654394) Binding of [3H]nitrendipine to calcium channel in rat cerebral cortex
- ChEMBL_42914 (CHEMBL654395) Binding of [3H]nitrendipine to calcium channel in rat heart membranes
- ChEMBL_462971 (CHEMBL928889) Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay
- ChEMBL_538845 (CHEMBL1033088) Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR
- ChEMBL_603504 (CHEMBL1068423) Inhibition of human T-type calcium channel alpha1G in HEK293 cells
- ChEMBL_661606 (CHEMBL1251540) Inhibition of rabbit sarcoplasmic reticulum calcium ATPase by ATP regeneration assay
- ChEMBL_664261 (CHEMBL1261768) Positive allosteric modulation of calcium sensing receptor by cell based assay
- ChEMBL_727149 (CHEMBL1687120) Antagonist activity against mGlu5 receptor assessed as inhibition of calcium mobilization
- ChEMBL_727155 (CHEMBL1687126) Antagonist activity at human TRPV1 assessed as inhibition of calcium influx
- ChEMBL_729863 (CHEMBL1695217) Antagonist activity at CCR5 assessed as inhibition of intracellular calcium mobilization
- ChEMBL_815533 (CHEMBL2025062) Agonist activity at human muscarinic M1 receptor by calcium mobilization assay
- ChEMBL_815535 (CHEMBL2025064) Agonist activity at human muscarinic M2 receptor by calcium mobilization assay
- ChEMBL_815537 (CHEMBL2025066) Agonist activity at human muscarinic M3 receptor by calcium mobilization assay
- ChEMBL_815538 (CHEMBL2025067) Antagonist activity at human muscarinic M2 receptor by calcium mobilization assay
- ChEMBL_815541 (CHEMBL2025070) Antagonist activity at human muscarinic M3 receptor by calcium mobilization assay
- ChEMBL_815543 (CHEMBL2025072) Agonist activity at human muscarinic M4 receptor by calcium mobilization assay
- ChEMBL_815545 (CHEMBL2025074) Antagonist activity at human muscarinic M4 receptor by calcium mobilization assay
- ChEMBL_815547 (CHEMBL2025076) Agonist activity at human muscarinic M5 receptor by calcium mobilization assay
- ChEMBL_815549 (CHEMBL2025078) Antagonist activity at human muscarinic M5 receptor by calcium mobilization assay
- ChEMBL_858563 (CHEMBL2166008) Antagonist activity at human muscarinic M5 receptor by calcium mobilization assay
- ChEMBL_858564 (CHEMBL2166009) Antagonist activity at human muscarinic M4 receptor by calcium mobilization assay
- ChEMBL_858565 (CHEMBL2166010) Antagonist activity at human muscarinic M2 receptor by calcium mobilization assay
- ChEMBL_858566 (CHEMBL2166011) Antagonist activity at human muscarinic M3 receptor by calcium mobilization assay
- ChEMBL_88346 (CHEMBL700005) Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophils
- ChEMBL_1765297 (CHEMBL4200544) Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
- ChEMBL_1765298 (CHEMBL4200545) Modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
- ChEMBL_1804301 (CHEMBL4276593) Agonist activity at dopamine D3 receptor (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 mins by calcium 4-dye based FLIPR assay
- ChEMBL_313070 (CHEMBL835875) In vitro antagonism of N-type calcium channels expressed in PC12 cells was determined as the increase in intracellular calcium influx in the presence of 10 uM nifedipine
- ChEMBL_629920 (CHEMBL1108384) Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs before glutamate challenge by calcium fluorescence assay
- ChEMBL_1776557 (CHEMBL4233549) Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in calcium flux measured every 2 secs for 90 secs by Calcium-3 dye based FLIPR assay
- ChEMBL_1804303 (CHEMBL4276595) Agonist activity at serotonin 5-HT1A receptor (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1804305 (CHEMBL4276597) Agonist activity at serotonin 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1804307 (CHEMBL4276599) Agonist activity at serotonin 5-HT6R receptor (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 mins by calcium 4-dye based FLIPR assay
- ChEMBL_2158153 (CHEMBL5042903) Antagonist activity at mouse MOR expressed in CHO cells assessed as inhibition of DAMGO-induced calcium mobilization preincubated for 60 mins measured after 15 mins by calcium mobilization assay
- ChEMBL_2240117 (CHEMBL5154013) Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for 15 mins by Fluo-4 AM calcium flux assay
- ChEMBL_489239 (CHEMBL989986) Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal calcium mobilization by calcium 3 assay
- ChEMBL_744536 (CHEMBL1772557) Partial antagonist activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs before glutamate challenge by calcium fluorescence assay
- ChEBML_141323 Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assay
- ChEBML_141325 Inhibition of N-type calcium channel (VSCC) in IMR-32 at 10 uM
- ChEBML_1685391 Activity at human M2 receptor assessed as increase in acetylcholine-induced calcium mobilization
- ChEBML_42915 Binding of [3H]nitrendipine to calcium channel in rat heart membranes was determined
- ChEBML_84953 Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a
- ChEMBL_141327 (CHEMBL752906) Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cells
- ChEMBL_141439 (CHEMBL751984) Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cells
- ChEMBL_1448349 (CHEMBL3376268) Agonist activity at muscarinic M1 receptor (unknown origin) by calcium mobilization assay
- ChEMBL_1448350 (CHEMBL3376269) Agonist activity at muscarinic M4 receptor (unknown origin) by calcium mobilization assay
- ChEMBL_1550577 (CHEMBL3762431) Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization
- ChEMBL_1550579 (CHEMBL3762433) Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization
- ChEMBL_1550598 (CHEMBL3762452) Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization
- ChEMBL_1576538 (CHEMBL3803978) Displacement of [3H]trifluoperazine from bovine brain CaM in presence of calcium
- ChEMBL_162531 (CHEMBL767435) Inhibition of purified mammalian brain calcium calmodulin dependent protein kinase (Ca calmod)
- ChEMBL_1758001 (CHEMBL4193009) Antagonist activity at 5-HT2A receptor (unknown origin) by calcium release assay
- ChEMBL_1758002 (CHEMBL4193010) Antagonist activity at 5-HT2B receptor (unknown origin) by calcium release assay
- ChEMBL_1758003 (CHEMBL4193011) Antagonist activity at 5-HT2C receptor (unknown origin) by calcium release assay
- ChEMBL_178933 (CHEMBL782876) Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranes
- ChEMBL_2016546 (CHEMBL4670124) Agonist activity at 5-HT2B receptor (unknown origin) by calcium mobilization assay
- ChEMBL_2020186 (CHEMBL4673999) Agonist activity at mouse GPR40 assessed as increase in intracellular calcium level
- ChEMBL_214400 (CHEMBL881932) Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cells
- ChEMBL_2151025 (CHEMBL5035487) Inhibition of PDE4 (unknown origin) in presence of calcium by colorimetric assay
- ChEMBL_2151026 (CHEMBL5035488) Inhibition of PDE4 (unknown origin) in absence of calcium by colorimetric assay
- ChEMBL_2153905 (CHEMBL5038452) Agonist activity at 5-HT2A receptor (unknown origin) by calcium flux assay
- ChEMBL_217675 (CHEMBL819969) Displacement of dihydropyridine (DHP) from the L-type calcium channel binding site
- ChEMBL_2214495 (CHEMBL5127627) Agonist activity at C57BL6/J mouse brain KOP by calcium mobilization assay
- ChEMBL_2215504 (CHEMBL5128636) Agonist activity at human mGlu4 receptor assessed as increase in calcium flux
- ChEMBL_2267542 Agonist activity at human GPR120 expressed in HEK293 cells assessed as calcium accumulation
- ChEMBL_2275373 Agonist activity at human D4R expressed in HEK293 cells by calcium flux assay
- ChEMBL_2315593 Inhibition of nAChR alpha7 receptor (unknown origin) assessed as inhibition of calcium flux
- ChEMBL_2350507 Inhibition of human P2X7 receptor transfected in HEK293 cells by calcium influx assay
- ChEMBL_2350508 Inhibition of rat P2X7 receptor transfected in HEK293 cells by calcium influx assay
- ChEMBL_322390 (CHEMBL856254) Inhibition of MIP-1beta stimulated calcium transients in CCR5-expressing CHO cells
- ChEMBL_329050 (CHEMBL863005) Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cells
- ChEMBL_329051 (CHEMBL863296) Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cells
- ChEMBL_341810 (CHEMBL865012) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK6
- ChEMBL_341812 (CHEMBL865014) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1
- ChEMBL_341813 (CHEMBL865015) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2
- ChEMBL_341814 (CHEMBL865016) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA3
- ChEMBL_341815 (CHEMBL865017) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA4
- ChEMBL_353887 (CHEMBL865034) Inhibition of MCH-mediated calcium release in whole IMR32 cells by FLIPR
- ChEMBL_397232 (CHEMBL864287) Activity at CCR2b by calcium flux based FLIPR assay in CHO cells
- ChEMBL_425252 (CHEMBL856829) Activity at human NR2A expressed in Ltk- cells by calcium flux assay
- ChEMBL_425687 (CHEMBL912003) Activity at metastin receptor expressed in HEK293 cells by measuring calcium release
- ChEMBL_42759 (CHEMBL653729) Inhibition of [3H]nitrendipine binding to calcium channels of guinea pig myocardium
- ChEMBL_42772 (CHEMBL660036) Inhibition of [3H]nitrendipine binding to calcium channels in rabbit cardiac muscle
- ChEMBL_42776 (CHEMBL660040) Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.
- ChEMBL_42922 (CHEMBL654565) Inhibition of [3H]nitrendipine binding to calcium channel of rat brain membranes.
- ChEMBL_456283 (CHEMBL888295) Antagonist activity at human CCR3 receptor assessed as inhibition of calcium flux
- ChEMBL_53180 (CHEMBL664575) Inhibition of [3H]nitrendipine binding to calcium channels in the rat brain.
- ChEMBL_544158 (CHEMBL1013439) Antagonist activity at EP1 receptor assessed as calcium mobilization by FLIPR assay
- ChEMBL_562556 (CHEMBL1014548) Agonist activity at human NTR1 assessed as increase in intracellular calcium concentration
- ChEMBL_566215 (CHEMBL963296) Agonist activity at NTR1 expressed in CHOK1 cells by calcium mobilization assay
- ChEMBL_572153 (CHEMBL1028509) Activation of Drosophila melanogaster ryanodine receptor assessed as induction of calcium mobilization
- ChEMBL_698556 (CHEMBL1647731) Inhibition of calmodulin assessed as inhibition of calmodulin-calcium-PDE1 complex formation
- ChEMBL_698557 (CHEMBL1647732) Inhibition of calmodulin assessed as inhibition of calmodulin-calcium-PDE4 complex formation
- ChEMBL_762018 (CHEMBL1815970) Antagonist activity at CXCR4 assessed as inhibition of SDF1-induced calcium mobilization
- ChEMBL_802795 (CHEMBL1953529) Inhibition of human CCR2-mediated intracellular calcium mobilization by cell based assay
- ChEMBL_876871 (CHEMBL2184465) Antagonist activity at human P2X7 receptor by cell-based calcium influx assay
- ChEMBL_876872 (CHEMBL2184466) Antagonist activity at human P2X3 receptor by cell-based calcium influx assay
- ChEMBL_876873 (CHEMBL2184467) Antagonist activity at human P2X2 receptor by cell-based calcium influx assay
- ChEMBL_876874 (CHEMBL2184468) Antagonist activity at human P2X1 receptor by cell-based calcium influx assay
- ChEMBL_876875 (CHEMBL2184469) Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assay
- ChEMBL_876876 (CHEMBL2184470) Antagonist activity at rat P2X4 receptor by cell-based calcium influx assay
- ChEMBL_92942 (CHEMBL706153) Inhibition of L-type calcium channels in GH-3 rat pituitary cells
- ChEMBL_945539 (CHEMBL2344016) Inhibition of T-type calcium channel Cav3.2 (unknown origin) by IONWORKS assay
- ChEBML_1613533 Inhibition of human T-type calcium channel Cav3.1 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential measured after 150 secs by QPatch assay
- ChEBML_1613535 Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential measured after 150 secs by QPatch assay
- ChEBML_1613536 Inhibition of human T-type calcium channel Cav3.3 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1804299 (CHEMBL4276591) Agonist activity at dopamine D2 receptor long isoform (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 min by calcium 4-dye based FLIPR assay
- ChEMBL_1804311 (CHEMBL4276603) Antagonist activity at dopamine D3 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of dopamine-induced calcium flux after 15 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1804317 (CHEMBL4276609) Antagonist activity at serotonin human 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium flux after 15 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1839471 (CHEMBL4339686) Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
- ChEMBL_1839472 (CHEMBL4339687) Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
- ChEMBL_1879035 (CHEMBL4380429) Antagonist activity at human EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
- ChEMBL_1879036 (CHEMBL4380430) Antagonist activity at mouse EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
- ChEMBL_1879037 (CHEMBL4380431) Antagonist activity at human EP1 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
- ChEMBL_1879038 (CHEMBL4380432) Antagonist activity at human EP2 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
- ChEMBL_1879039 (CHEMBL4380433) Antagonist activity at human EP3 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
- ChEMBL_2053967 (CHEMBL4708968) Antagonist activity at 5-HT2A receptor (unknown origin) assessed as decrease in intracellular calcium flux preincubated with calcium followed by compound challenge and measured after 10 mins by FLIPR method
- ChEMBL_2134240 (CHEMBL4843850) Antagonist activity at human PAR4 expressed in Ga15-HEK293 cells assessed as reduction in PAR4 AP AYPGKF-NH2-induced cytosolic calcium incubated for 24 hrs by FLIPR - calcium mobilization assay
- ChEMBL_2134241 (CHEMBL4843851) Antagonist activity at human PAR1 expressed in Ga15-HEK293 cells assessed as reduction in PAR1 AP SFFLRR-NH2-induced cytosolic calcium incubated for 24 hrs by FLIPR - calcium mobilization assay
- ChEMBL_744538 (CHEMBL1772559) Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubated for 140 secs before glutamate challenge by calcium fluorescence assay
- ChEMBL_744540 (CHEMBL1772561) Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs before glutamate challenge by calcium fluorescence assay
- ChEMBL_1613523 (CHEMBL3855323) Inhibition of human T-type calcium channel Cav3.3 expressed in CHO cells assessed as inhibition of calcium tail current at -60 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1613532 (CHEMBL3855332) Inhibition of human T-type calcium channel Cav3.1 expressed in CHO cells assessed as inhibition of calcium tail current at -60 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1613534 (CHEMBL3855334) Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -60 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1613535 (CHEMBL3855335) Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1613536 (CHEMBL3855336) Inhibition of human T-type calcium channel Cav3.3 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential measured after 150 secs by QPatch assay
- ChEMBL_1677403 (CHEMBL4027546) Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 mins by calcium 4 dye-based FLIPR assay
- ChEMBL_1776556 (CHEMBL4233548) Agonist activity at human GPR120 expressed in baculovirus infected sf9 cells assessed as increase in calcium flux measured every 1 sec for 60 secs by Calcium plus dye based FLIPR assay
- ChEMBL_1804313 (CHEMBL4276605) Antagonist activity at serotonin 5-HT1A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium flux after 15 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1804315 (CHEMBL4276607) Antagonist activity at serotonin 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium flux after 15 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1933659 (CHEMBL4479311) Antagonist activity at human P2X1 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx preincubated for 30 mins prior to ATP-stimulation by calcium influx assay
- ChEMBL_1933662 (CHEMBL4479314) Antagonist activity at human P2X2 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx preincubated for 30 mins prior to ATP-stimulation by calcium influx assay
- ChEMBL_1933664 (CHEMBL4479316) Antagonist activity at human P2X3 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx preincubated for 30 mins prior to ATP-stimulation by calcium influx assay
- ChEMBL_1933667 (CHEMBL4479319) Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx preincubated for 30 mins prior to ATP-stimulation by calcium influx assay
- ChEMBL_2050027 (CHEMBL4704726) Agonist activity at human FFA4 expressed in HEK293 cells assessed as stimulation of intracellular calcium mobilization measured at every 1 secs for 60 secs by Calcium-3 dye based FLIPR assay
- ChEMBL_2085008 (CHEMBL4766271) Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measured over 3 mins by calcium 4 dye based FLIPR assay
- ChEMBL_2146861 (CHEMBL5031207) Antagonist activity at human CCR5 receptor expressed in HEK293 cells co-expressing Galpha15 assessed as inhibition of RNATES-induced intracellular calcium flux measured after 10 mins by FLIPR calcium mobilization assay
- ChEMBL_2158154 (CHEMBL5042904) Agonist activity at mouse MOR expressed in CHO cells coexpressing Gqi5 assessed as inhibition of DAMGO-induced calcium mobilization preincubated for 60 mins measured after 15 mins by calcium mobilization assay
- ChEMBL_744534 (CHEMBL1772555) Ago-Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubated for 140 secs before glutamate challenge by calcium fluorescence assay
- ChEBML_198268 Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles
- ChEBML_42745 Inhibition of voltage sensitive calcium channel of embryonic chick dorsal root ganglion (DRG) cells
- ChEBML_42766 Inhibition of [3H]PN-200110 binding to Calcium channel in guinea pig heart membrane
- ChEBML_42767 Displacement of [3H]diltiazem from L-type calcium channel of guinea pig striated muscle
- ChEMBL_1361426 (CHEMBL3294050) Agonist activity at human GPR40 expressed in CHO cells by calcium flux assay
- ChEMBL_1361427 (CHEMBL3294051) Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assay
- ChEMBL_1442874 (CHEMBL3377152) Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay
- ChEMBL_1454702 (CHEMBL3362621) Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay
- ChEMBL_1454703 (CHEMBL3362622) Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay
- ChEMBL_1454706 (CHEMBL3362625) Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_1454707 (CHEMBL3362626) Agonist activity at mouse NMUR2 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_1522009 (CHEMBL3627116) Agonist activity at human OX1R expressed in CHOK1 cells by calcium mobilization assay
- ChEMBL_1555507 (CHEMBL3768089) Binding affinity to recombinant rat calcium loaded S100-B by isothermal titration calorimetry
- ChEMBL_1555508 (CHEMBL3768090) Binding affinity to recombinant rat calcium loaded S100-B by fluorescence spectrophotometric analysis
- ChEMBL_1577058 (CHEMBL3807104) Agonist activity at human GPR40 expressed in CHO cells by calcium influx assay
- ChEMBL_1589193 (CHEMBL3829966) Antagonist activity at calcium sensing receptor (unknown origin) by cell based FLIPR assay
- ChEMBL_1621027 (CHEMBL3863310) Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced calcium flux
- ChEMBL_1621028 (CHEMBL3863311) Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced calcium flux
- ChEMBL_1621029 (CHEMBL3863312) Antagonist activity at human CCR5 assessed as inhibition of RANTES-induced calcium flux
- ChEMBL_1621030 (CHEMBL3863313) Antagonist activity at human CXCR3 assessed as inhibition of IP10-induced calcium flux
- ChEMBL_1621031 (CHEMBL3863314) Antagonist activity at human CXCR2 assessed as inhibition of GROalpha-induced calcium flux
- ChEMBL_1720891 (CHEMBL4135891) Agonist activity at FPR2 in human neutrophils assessed as induction of calcium mobilization
- ChEMBL_197572 (CHEMBL804024) Inhibition of hSK1 calcium activated potassium channel (SKCa channel); Range is 1-2
- ChEMBL_1986382 (CHEMBL4619929) Agonist activity at 5HT1A receptor (unknown origin) by calcium-dye based FLIPR assay
- ChEMBL_2071740 (CHEMBL4727274) Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay
- ChEMBL_2071753 (CHEMBL4727287) Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay
- ChEMBL_2077205 (CHEMBL4732996) Agonist activity at CCKBR in human NCI-H345 cells assessed as calcium release
- ChEMBL_214942 (CHEMBL819393) Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.
- ChEMBL_217679 (CHEMBL819973) Displacement of [3H]nitrendipine from calcium channel receptors (CCRs) from rat cortex homogenate
- ChEMBL_2215510 (CHEMBL5128642) Inhibition of Voltage-dependent T-type calcium channel (unknown origin) by HTS assay
- ChEMBL_2267544 Agonist activity at human GPR120 expressed in CHO-K1 cells assessed as calcium accumulation
- ChEMBL_2281730 Antagonist activity at human LPA2 receptor assessed as inhibition of LPS-induced calcium release
- ChEMBL_2350503 Inhibition of human P2X7 receptor in HEK cells by fluorescence based calcium influx assay
- ChEMBL_2350504 Inhibition of mouse P2X7 receptor in HEK cells by fluorescence based calcium influx assay
- ChEMBL_306305 (CHEMBL828597) Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor
- ChEMBL_310320 (CHEMBL833276) Serotonin 5-HT2A receptor-mediated intracellular calcium [Ca2+] mobilization in rat A7r5 cells
- ChEMBL_337506 (CHEMBL861440) Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assay
- ChEMBL_337507 (CHEMBL861441) Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assay
- ChEMBL_337509 (CHEMBL861588) Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assay
- ChEMBL_338249 (CHEMBL868347) Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase
- ChEMBL_338250 (CHEMBL868348) Activity against rat P2Y2-GFP transfected in HEK293 cells by intracellular calcium increase
- ChEMBL_338251 (CHEMBL867177) Activity against human P2Y1-GFP expressed in 1321N1 cells by intracellular calcium increase
- ChEMBL_338252 (CHEMBL867178) Activity against human P2Y2-GFP expressed in A549 cells by intracellular calcium increase
- ChEMBL_341800 (CHEMBL865002) Induction of calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assay
- ChEMBL_348348 (CHEMBL866241) Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membrane
- ChEMBL_348644 (CHEMBL866258) Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membrane
- ChEMBL_351709 (CHEMBL870098) Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyte
- ChEMBL_351710 (CHEMBL870099) Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human whole blood
- ChEMBL_365289 (CHEMBL862275) Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cells
- ChEMBL_365290 (CHEMBL862276) Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cells
- ChEMBL_365291 (CHEMBL862277) Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cells
- ChEMBL_385201 (CHEMBL868013) Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay
- ChEMBL_385202 (CHEMBL868014) Activity at human LPA2 receptor expressed in RH7777 cells by calcium mobilization assay
- ChEMBL_385203 (CHEMBL868015) Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assay
- ChEMBL_400286 (CHEMBL913220) Activity at rat mGluR1 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400287 (CHEMBL912659) Activity at rat mGluR2 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400288 (CHEMBL912661) Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400289 (CHEMBL912662) Activity at rat mGluR5 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400290 (CHEMBL912663) Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400291 (CHEMBL912664) Activity at rat mGluR7 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_400292 (CHEMBL912665) Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HEK293 cells
- ChEMBL_421232 (CHEMBL856554) Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1
- ChEMBL_421987 (CHEMBL856549) Inhibition of MCH-mediated calcium release by CHO cells expressing human MCH-R1
- ChEMBL_425251 (CHEMBL856828) Antagonist activity at human NR2B expressed in Ltk- cells by calcium flux assay
- ChEMBL_42915 (CHEMBL654396) Binding of [3H]nitrendipine to calcium channel in rat heart membranes was determined
- ChEMBL_438655 (CHEMBL888986) Antagonist activity at human CXCR3 assessed as inhibition of MIG-induced calcium mobilization
- ChEMBL_438663 (CHEMBL888994) Antagonist activity at human CXCR3 assessed as inhibition of ITAC-induced calcium mobilization
- ChEMBL_439840 (CHEMBL890161) Agonist activity at GPR54 expressed in CHO cells assessed as intracellular calcium mobilization
- ChEMBL_460851 (CHEMBL943866) Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux
- ChEMBL_461949 (CHEMBL945737) Antagonist activity at rat TRPV1 assessed as inhibition of capsaicin-induced calcium mobilization
- ChEMBL_523542 (CHEMBL1001556) Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_532531 (CHEMBL976100) Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx
- ChEMBL_559838 (CHEMBL1021519) Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_599549 (CHEMBL1038359) Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium level
- ChEMBL_605403 (CHEMBL1073397) Agonist activity at human GPR14 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_619927 (CHEMBL1113138) Antagonist activity at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_619931 (CHEMBL1113142) Antagonist activity at rat mGluR1 expressed in BHK cells by calcium mobilization assay
- ChEMBL_643029 (CHEMBL1176543) Agonist activity at rat NTR1 expressed in LTK cells assessed as calcium mobilization
- ChEMBL_747688 (CHEMBL1780797) Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring
- ChEMBL_750426 (CHEMBL1785978) Negative allosteric modulator activity at rat calcium sensing receptor expressed in HEK cells
- ChEMBL_762019 (CHEMBL1815971) Antagonist activity at human CCR5 assessed as inhibition of RANTES-induced calcium mobilization
- ChEMBL_762022 (CHEMBL1816014) Antagonist activity at rat CCR5 assessed as inhibition of RANTES-induced calcium mobilization
- ChEMBL_762023 (CHEMBL1816015) Antagonist activity at rabbit CCR5 assessed as inhibition of RANTES-induced calcium mobilization
- ChEMBL_770872 (CHEMBL1837820) Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay
- ChEMBL_770873 (CHEMBL1837821) Antagonist activity at human NPY1 receptor assessed as calcium mobilization by FLIPR assay
- ChEMBL_770874 (CHEMBL1837822) Antagonist activity at human NPY2 receptor assessed as calcium mobilization by FLIPR assay
- ChEMBL_770875 (CHEMBL1837823) Antagonist activity at human NPY4 receptor assessed as calcium mobilization by FLIPR assay
- ChEMBL_818581 (CHEMBL2032868) Antagonist activity at serotonin 5HT2C receptor assessed as blockage of intracellular calcium mobilization
- ChEMBL_819768 (CHEMBL2034280) Agonist activity at human SIP3 receptor assessed as calcium mobilization by GeneBLAzer assay
- ChEMBL_830096 (CHEMBL2061887) Agonist activity at rat TRPV1 expressed in CHO cells assessed as calcium uptake
- ChEMBL_830237 (CHEMBL2060788) Agonist activity at GPR120 expressed in Flp-In TREx293 cells by calcium assay
- ChEMBL_830244 (CHEMBL2060795) Agonist activity at FFAR1 expressed in Flp-In TREx293 cells by calcium assay
- ChEMBL_84953 (CHEMBL697754) Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a
- ChEMBL_86312 (CHEMBL696464) Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay
- ChEMBL_903202 (CHEMBL3049062) Inhibition of L-type calcium channel in Rattus norvegicus (rat) heart artery myocytes
- ChEMBL_92775 (CHEMBL700075) Inhibition of [3H](+)-PN200-110 binding to calcium channels of rat heart membranes.
- ChEMBL_92785 (CHEMBL704172) Competitive binding of 3[H]+isradipine to calcium channels of rat cardiac membranes
- ChEMBL_92943 (CHEMBL706154) Inhibition of [3H](+)-PN200-110 binding to calcium channels of rat heart membranes.
- ChEMBL_934123 (CHEMBL2318876) Positive allosteric modulator activity at human muscarinic M1 receptor by calcium mobilization assay
- ChEMBL_959727 (CHEMBL2383047) Agonist activity at human GPR40 transfected in CHO cells by calcium flux assay
- ChEMBL_1762557 (CHEMBL4197804) Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds followed by CXCL12 stimulation by calcium 4 dye-based FLIPR assay
- ChEMBL_1804309 (CHEMBL4276601) Antagonist activity at dopamine D2 receptor long isoform (unknown origin) expressed in HEK293 cells assessed as inhibition of dopamine-induced calcium flux after 15 mins by calcium 4-dye based FLIPR assay
- ChEMBL_1846642 (CHEMBL4347183) Inhibition of Sprague-Dawley rat 5-LOX assessed as calcium ionophore A23187-stimulated LTB4 production preincubated for 30 mins followed by calcium ionophore A23187 addition and measured after 30 mins by ELISA
- ChEMBL_1850627 (CHEMBL4351251) Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 30 mins followed by calcium ionophore stimulation and measured after 20 mins by EIA
- ChEMBL_1850628 (CHEMBL4351252) Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 4 hrs followed by calcium ionophore stimulation and measured after 20 mins by EIA
- ChEMBL_1993677 (CHEMBL4627572) Agonist activity at human AGTR1 stably expressed in CHO cells assessed as increase in intracellular calcium mobilization measured at 1 sec intervals for 90 sec by calcium 5 dye based FLIPR assay
- ChEMBL_2050026 (CHEMBL4704725) Agonist activity at human FFA1 expressed in HEK293 cells assessed as stimulation of intracellular calcium mobilization measured at 2 secs time interval for 90 secs by Calcium-3 dye based FLIPR assay
- ChEMBL_2134242 (CHEMBL4843852) Antagonist activity at human PAR2 expressed in Ga15-HEK293 cells assessed as reduction in PAR2 AP 2-furoyl-LIGRLO-NH2-induced cytosolic calcium incubated for 24 hrs by FLIPR - calcium mobilization assay
- ChEMBL_2307087 Antagonist activity at mouse mu opioid receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of DAMGO induced increase in intracellular calcium flux incubated for 15 mins by Calcium flux assay
- ChEBML_1734263 Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDS1alpha-induced calcium flux pretreated for 25 mins followed by SDS1alpha addition measured for 90 secs by calcium-dye based assay
- ChEBML_1734264 Antagonist activity at mAChR in human CCRF-CEM cells assessed as inhibition of acetylcholine-induced calcium flux pretreated for 25 mins followed by acetylcholine addition measured for 90 secs by calcium-dye based assay
- ChEMBL_1839473 (CHEMBL4339688) Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux at 100 uM by calcium 5/6 dye based FLIPR assay
- ChEMBL_1924266 (CHEMBL4427222) Antagonist activity at rat P2X7 receptor expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization incubated for 30 mins measured after 180 seconds by calcium-4 dye based FLIPR assay
- ChEMBL_2297445 Positive allosteric modulator activity at rat mGlu5 in human HEK cells assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_2365556 Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium leak in presence of calcium chloride by time-lapse fluorescence analysis
- ChEMBL_819282 (CHEMBL2032639) Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular calcium concentration preincubated for 4 to 5 mins before KCl challenge
- ChEBML_141321 In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells
- ChEBML_156048 Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2.
- ChEBML_1679911 Positive allosteric modulation of rat M4 receptor assessed as increase in acetylcholine-induced calcium mobilization
- ChEBML_214539 Inhibition of 1 nM AVP-induced calcium mobilisation in cells expressing human vasopressin V1a receptor
- ChEMBL_1279974 (CHEMBL3096609) Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells by FDSS assay
- ChEMBL_1454700 (CHEMBL3362619) Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay
- ChEMBL_1454701 (CHEMBL3362620) Partial agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay
- ChEMBL_1459230 (CHEMBL3367256) Agonist activity at rat nAChR alpha7 expressed in GH4C1 cells by fluorescent calcium assay
- ChEMBL_1464916 (CHEMBL3404386) Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_1464920 (CHEMBL3404390) Negative allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_1472897 (CHEMBL3419951) Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium mobilization
- ChEMBL_1472898 (CHEMBL3419952) Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium mobilization
- ChEMBL_1475134 (CHEMBL3424812) Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells by fluorescent calcium assay
- ChEMBL_1517380 (CHEMBL3620961) Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assay
- ChEMBL_1527423 (CHEMBL3636798) Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as calcium mobilization
- ChEMBL_1527446 (CHEMBL3636977) Positive allosteric modulation of rat mGlu5 assessed as calcium mobilization by cell-based assay
- ChEMBL_154990 (CHEMBL765342) Displacement of [3H]-diltiazem from L-type calcium channel of bovine frontal cortex membranes.
- ChEMBL_154991 (CHEMBL765343) Displacement of [3H]nitrendipine from L-type calcium channel of bovine frontal cortex membranes.
- ChEMBL_1553735 (CHEMBL3766803) Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assay
- ChEMBL_1553736 (CHEMBL3766804) Agonist activity at human recombinant DOR expressed in CHO cells by calcium mobilization assay
- ChEMBL_1553737 (CHEMBL3766805) Agonist activity at human recombinant KOR expressed in CHO cells by calcium mobilization assay
- ChEMBL_1559987 (CHEMBL3777023) Displacement of [125I]apamin from rat cerebral cortex small conductance calcium-activated potassium channel
- ChEMBL_1572761 (CHEMBL3804270) Agonist activity at human GPR40 expressed in CHO cells by FLIPR calcium flux assay
- ChEMBL_162632 (CHEMBL878682) Inhibition of 2-[125I]iodomelatonin stimulated calcium dependent dopamine release from the rabbit retina.
- ChEMBL_1754034 (CHEMBL4188794) Agonist activity at GPR120 in human HT-29 cells assessed as intracellular calcium flux
- ChEMBL_1766429 (CHEMBL4201676) Agonist activity at human OTR stably expressed in HEK cells by calcium flux assay
- ChEMBL_177580 (CHEMBL783655) Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortex
- ChEMBL_1785284 (CHEMBL4256801) Antagonist activity at TRPM8 (unknown origin) assessed as reduction in menthol-induced calcium influx
- ChEMBL_1795011 (CHEMBL4267128) Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay
- ChEMBL_1832093 (CHEMBL4332101) Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay
- ChEMBL_198268 (CHEMBL802440) Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles
- ChEMBL_2071752 (CHEMBL4727286) Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay
- ChEMBL_210769 (CHEMBL815740) Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor
- ChEMBL_214797 (CHEMBL815533) Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex
- ChEMBL_2185287 (CHEMBL5097369) Agonist activity at FFAR1 (unknown origin) expressed in CHO cells by FLIPR calcium assay
- ChEMBL_2214401 (CHEMBL5127533) Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assay
- ChEMBL_2216873 (CHEMBL5130005) Antagonist activity at CXCR3 (unknown origin) in presence of CXCL9 by calcium FLIPR assay
- ChEMBL_2216874 (CHEMBL5130006) Antagonist activity at CXCR3 (unknown origin) in presence of CXCL10 by calcium FLIPR assay
- ChEMBL_2216875 (CHEMBL5130007) Antagonist activity at CXCR3 (unknown origin) in presence of CXCL11 by calcium FLIPR assay
- ChEMBL_2283675 Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell based calcium assay
- ChEMBL_303540 (CHEMBL839653) Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortex
- ChEMBL_306207 (CHEMBL830165) Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortex
- ChEMBL_310398 (CHEMBL834482) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor
- ChEMBL_310430 (CHEMBL834056) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor
- ChEMBL_310431 (CHEMBL834057) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor
- ChEMBL_310432 (CHEMBL834058) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor
- ChEMBL_312380 (CHEMBL836738) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor
- ChEMBL_312535 (CHEMBL832578) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor
- ChEMBL_312536 (CHEMBL832579) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor
- ChEMBL_312537 (CHEMBL832580) Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor
- ChEMBL_329318 (CHEMBL863541) Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells
- ChEMBL_332923 (CHEMBL854074) [3H]Gabapentin binding in human A710 membrane expressing alpha-2delta subunit of calcium channel
- ChEMBL_335548 (CHEMBL859414) Displacement of [3H]L-leucine from alpha-2delta containing calcium channel in murine brain
- ChEMBL_361060 (CHEMBL859182) Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes
- ChEMBL_417944 (CHEMBL912404) Activity at human D1 dopamine receptor expressed in HEK293 cells by calcium fluorescence assay
- ChEMBL_417945 (CHEMBL912405) Activity at human D2L dopamine receptor expressed in HEK293 cells by calcium fluorescence assay
- ChEMBL_417946 (CHEMBL912406) Activity at human D5 dopamine receptor expressed in HEK293 cells by calcium fluorescence assay
- ChEMBL_421374 (CHEMBL856556) Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1
- ChEMBL_42762 (CHEMBL653732) Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.
- ChEMBL_42763 (CHEMBL653733) Inhibition of [3H]-PN-200110 binding to Calcium channel in guinea pig heart membrane.
- ChEMBL_42764 (CHEMBL653734) Inhibition of [3H]PN-200110 binding to Calcium channel in guinea pig ileum membrane
- ChEMBL_42765 (CHEMBL659157) Inhibition of [3H]PN-200110 binding to Calcium channel in guinea pig ileum membrane.
- ChEMBL_438084 (CHEMBL887215) Inhibition of human recombinant TP receptor expressed in CHO cells by calcium mobilisation assay
- ChEMBL_438365 (CHEMBL887467) Activity at human kappa opioid receptor expressed in HEK293 cells as intracellular calcium mobilization
- ChEMBL_443085 (CHEMBL892216) Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentration
- ChEMBL_443086 (CHEMBL892217) Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentration
- ChEMBL_449273 (CHEMBL899535) Agonist activity at PAR2 expressed in human HT29 cells assessed as intracellular calcium release
- ChEMBL_450806 (CHEMBL899891) Antagonist activity at CCR2 expressed in THP1 cells assessed as MCP1-induced calcium flux
- ChEMBL_451010 (CHEMBL900091) Agonist activity at P2Y11 receptor expressed in 1321N1 cells assessed as cytosolic calcium level
- ChEMBL_451014 (CHEMBL900095) Agonist activity at P2Y1 receptor expressed in 1321N1 cells assessed as cytosolic calcium level
- ChEMBL_451015 (CHEMBL900096) Agonist activity at P2Y2 receptor expressed in 1321N1 cells assessed as cytosolic calcium level
- ChEMBL_453038 (CHEMBL902185) Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake
- ChEMBL_463782 (CHEMBL932171) Agonist activity at P2Y2 receptor expressed in human 1321 cells by calcium mobilization assay
- ChEMBL_463783 (CHEMBL932172) Agonist activity at P2Y6 receptor expressed in human 1321 cells by calcium mobilization assay
- ChEMBL_467201 (CHEMBL922514) Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_467203 (CHEMBL928074) Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_467205 (CHEMBL928076) Activity at rat cloned iGluR3 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_467207 (CHEMBL928078) Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_467209 (CHEMBL928080) Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_467211 (CHEMBL928082) Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay
- ChEMBL_480124 (CHEMBL923764) Antagonist activity at human GnRHR assessed as inhibition of calcium flux by IP3 assay
- ChEMBL_487959 (CHEMBL1013090) Activity at rat mGluR1 expressed in HEK293 cells assessed as calcium mobilization by FLIPR
- ChEMBL_487960 (CHEMBL1013091) Activity at rat mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR
- ChEMBL_487961 (CHEMBL1013092) Activity at rat mGluR2 expressed in CHO cells assessed as calcium mobilization by FLIPR
- ChEMBL_492975 (CHEMBL949441) Agonist activity at human FFA1 expressed in human 1321N1 cells by calcium fluorescence assay
- ChEMBL_493861 (CHEMBL943269) Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake
- ChEMBL_532532 (CHEMBL976968) Antagonist activity at human TRPV1 assessed as inhibition of low pH-induced calcium influx
- ChEMBL_542755 (CHEMBL1016811) Antagonist activity at TRPV1 in rat DRG neuron assessed as inhibition of calcium uptake
- ChEMBL_566265 (CHEMBL953568) Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells by calcium influx assay
- ChEMBL_596923 (CHEMBL1048864) Activation of human TAAR1 expressed in CHOK1 cells coexpressing Galpha16 assessed as calcium accumulation
- ChEMBL_625831 (CHEMBL1109767) Antagonist activity at OX1 receptor assessed as inhibition of calcium flux by FLIPR assay
- ChEMBL_625832 (CHEMBL1109768) Antagonist activity at OX2 receptor assessed as inhibition of calcium flux by FLIPR assay
- ChEMBL_642626 (CHEMBL1176769) Antagonist activity at human GPR54 receptor assessed as inhibition of metastin-induced calcium mobilization
- ChEMBL_643985 (CHEMBL1211884) Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry
- ChEMBL_648800 (CHEMBL1220639) Antagonist activity at GPR30 in human SKBr3 cells assessed as inhibition of calcium mobilization
- ChEMBL_745344 (CHEMBL1775464) Allosteric modulation at rat M1 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_750427 (CHEMBL1785979) Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cells
- ChEMBL_768782 (CHEMBL1831764) Positive allosteric modulation of mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobilization
- ChEMBL_768783 (CHEMBL1831765) Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilization
- ChEMBL_768784 (CHEMBL1831766) Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization
- ChEMBL_768785 (CHEMBL1831767) Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilization
- ChEMBL_768786 (CHEMBL1831768) Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization
- ChEMBL_800687 (CHEMBL1947809) Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assay
- ChEMBL_818502 (CHEMBL2032594) Antagonist activity at mouse MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization
- ChEMBL_818575 (CHEMBL2032862) Antagonist activity at rat MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization
- ChEMBL_818577 (CHEMBL2032864) Antagonist activity at human MCHR2 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization
- ChEMBL_851730 (CHEMBL2156072) Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization
- ChEMBL_878506 (CHEMBL2187791) Inhibition of Cav1.2 assessed as inhibition of calcium flux by cell based FLIPR assay
- ChEMBL_937320 (CHEMBL2319083) Partial agonist activity at human muscarinic M5 receptor expressed in CHO cells calcium response
- ChEMBL_937321 (CHEMBL2319084) Partial agonist activity at human muscarinic M4 receptor expressed in CHO cells calcium response
- ChEMBL_937322 (CHEMBL2319085) Partial agonist activity at human muscarinic M3 receptor expressed in CHO cells calcium response
- ChEMBL_937323 (CHEMBL2319086) Partial agonist activity at human muscarinic M2 receptor expressed in CHO cells calcium response
- ChEMBL_937325 (CHEMBL2319088) Partial agonist activity at human muscarinic M1 receptor expressed in CHO cells calcium response
- ChEMBL_937330 (CHEMBL2319093) Partial agonist activity at rat muscarinic M5 receptor expressed in CHO cells calcium response
- ChEMBL_937331 (CHEMBL2319094) Partial agonist activity at rat muscarinic M4 receptor expressed in CHO cells calcium response
- ChEMBL_937332 (CHEMBL2319366) Partial agonist activity at rat muscarinic M3 receptor expressed in CHO cells calcium response
- ChEMBL_937333 (CHEMBL2319367) Partial agonist activity at rat muscarinic M2 receptor expressed in CHO cells calcium response
- ChEMBL_937601 (CHEMBL2321070) Partial agonist activity at rat muscarinic M1 receptor expressed in CHO cells calcium response
- ChEMBL_981749 (CHEMBL2426830) Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assay
- ChEBML_1628579 Positive allosteric modulation of human GluA2 receptor flop isoform assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay
- ChEBML_1628582 Positive allosteric modulation of GluN1/GluN2C receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay
- ChEBML_1628587 Positive allosteric modulation of GluN1/GluN2D receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay
- ChEMBL_1502264 (CHEMBL3591343) Antagonist activity against human CCR2B expressed in Chem-1 cells assessed as inhibition of human CCL2-induced intracellular calcium flux incubated for 10 mins by Fluo-4 AM dye based intracellular calcium flux assay
- ChEMBL_1734263 (CHEMBL4149799) Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDS1alpha-induced calcium flux pretreated for 25 mins followed by SDS1alpha addition measured for 90 secs by calcium-dye based assay
- ChEMBL_1734264 (CHEMBL4149800) Antagonist activity at mAChR in human CCRF-CEM cells assessed as inhibition of acetylcholine-induced calcium flux pretreated for 25 mins followed by acetylcholine addition measured for 90 secs by calcium-dye based assay
- ChEMBL_1741062 (CHEMBL4156812) Antagonist activity at mAChR in human CCRF-CEM cells assessed as inhibition of acetylcholine-induced calcium release preincubated for 25 mins followed by acetylcholine stimulation and measured for 90 secs by calcium flux assay
- ChEMBL_1924265 (CHEMBL4427221) Antagonist activity at human recombinant P2X7 receptor expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization incubated for 30 mins measured after 180 seconds by calcium-4 dye based FLIPR assay
- ChEMBL_2297448 Positive allosteric modulator activity at rat mGlu1 in human HEK cells assessed assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_901282 (CHEMBL3052049) Inhibition of L-type calcium channel in neonatal rat cortical neurons assessed as inhibition of veratridine-induced intracellular calcium level incubated for 30 min followed by veratridine induction for 2 min by fluorimetric analysis
- ChEMBL_946142 (CHEMBL2343544) Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incubated for 30 mins prior to nicotine-induction by calcium-4 based FLIPR analysis
- ChEMBL_1628577 (CHEMBL3871162) Positive allosteric modulation of human GluA2 receptor flip isoform assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay
- ChEMBL_1628579 (CHEMBL3871164) Positive allosteric modulation of human GluA2 receptor flop isoform assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay
- ChEMBL_1690092 (CHEMBL4040662) Antagonist activity at human PAR1 expressed in HEK293 cells co-expressing Galpha15 assessed as inhibition of haTRAP-induced calcium mobilization preincubated for 15 mins followed by haTRAP addition by calcium-4 dye based FLIPR assay
- ChEMBL_1706757 (CHEMBL4057990) Inhibition of 5-LOX in Sprague Dawley rat Leukocytes assessed as reduction in calcium ionophore A23187-induced LTB4 production preincubated for 30 mins followed by calcium ionophore A23187 addition measured after 30 mins by ELISA
- ChEMBL_1729032 (CHEMBL4144310) Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDF1alpha-induced calcium flux pretreated for 25 mins followed by SDF1alpha addition measured for 90 secs by calcium dye-based fluorescence assay
- ChEMBL_1809606 (CHEMBL4309066) Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx preincubated for 30 mins followed by glutamate addition by calcium-5 dye based fluorometric assay
- ChEMBL_1996547 (CHEMBL4630442) Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interval for 45 secs by calcium 6 dye-based FLIPR assay
- ChEMBL_2092195 (CHEMBL4773458) Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced cytosolic calcium flux preincubated for 20 mins followed by CXCL12 addition by calcium 4 dye based FLIPR TETRA analysis
- ChEMBL_2441817 Inhibition of LTA4H in human whole blood assessed as calcium ionophore A23187-stimulated LTB4 release preincubated with compound for 4 hrs followed by calcium ionophore A23187 induction and measured after 15 mins by competitive immuno assay
- ChEMBL_936852 (CHEMBL2320734) Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calcium ionophore challenge measured after 10 to 30 mins by enzyme immunoassay
- ChEBML_4175 Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophilic leukemia cells(RBL-1)
- ChEBML_42758 Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranes
- ChEMBL_1362009 (CHEMBL3294080) Positive allosteric modulation of rat mGluR3 receptor expressed in TREx293 cells by calcium mobilization assay
- ChEMBL_1362011 (CHEMBL3294082) Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293A cells by calcium mobilization assay
- ChEMBL_141321 (CHEMBL752900) In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells
- ChEMBL_141322 (CHEMBL752901) In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells
- ChEMBL_1451954 (CHEMBL3363398) Negative allosteric modulator activity at human mGlu5 assessed as reduction in glutamate-induced calcium mobilization
- ChEMBL_1455275 (CHEMBL3362281) Antagonist activity at human adrenergic alpha1B receptor assessed as intracellular calcium by summary (Abse5) assay
- ChEMBL_1468235 (CHEMBL3411778) Agonist activity at CB1 receptor (unknown origin) expressed in CHO cells by calcium mobilization assay
- ChEMBL_1468236 (CHEMBL3411779) Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells by calcium mobilization assay
- ChEMBL_147560 (CHEMBL751759) Antagonistic activity against P2X7 receptor measured as the ATP dependent calcium influx in human monocytes
- ChEMBL_1499284 (CHEMBL3583166) Antagonist activity at GHSR1a (unknown origin) assessed as inhibition of ghrelin-induced intracellular calcium mobilization
- ChEMBL_1511556 (CHEMBL3607056) Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by calcium mobilization assay
- ChEMBL_154989 (CHEMBL765341) Displacement of [3H]desmethoxy-verapamil from L-type calcium channel of bovine frontal cortex membranes
- ChEMBL_1555504 (CHEMBL3768086) Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis
- ChEMBL_156048 (CHEMBL760624) Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2.
- ChEMBL_1573208 (CHEMBL3803186) Positive allosteric modulation of human mGlu1 receptor assessed as increase in glutamate-induced calcium mobilization
- ChEMBL_1573383 (CHEMBL3804545) Positive allosteric modulation of rat mGlu1 receptor assessed as increase in glutamate-induced calcium mobilization
- ChEMBL_1577059 (CHEMBL3807105) Agonist activity at human GPR41 (unknown origin) expressed in CHO cells by calcium influx assay
- ChEMBL_1577060 (CHEMBL3807106) Agonist activity at human GPR43 (unknown origin) expressed in CHO cells by calcium influx assay
- ChEMBL_1577061 (CHEMBL3807107) Agonist activity at human GPR120 (unknown origin) expressed in CHO cells by calcium influx assay
- ChEMBL_1578996 (CHEMBL3810852) Positive allosteric modulation of human mGlu4 receptor assessed as increase in glutamate-induced calcium mobilization
- ChEMBL_1579474 (CHEMBL3810543) Positive allosteric modulation of human M1 receptor expressed in CHOK1 cells by calcium mobilization assay
- ChEMBL_1579475 (CHEMBL3810544) Positive allosteric modulation of human M5 receptor expressed in CHOK1 cells by calcium mobilization assay
- ChEMBL_1589779 (CHEMBL3830331) Agonist activity at GPR40 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_1589781 (CHEMBL3830333) Agonist activity at GPR41 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_1589783 (CHEMBL3830335) Agonist activity at GPR119 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_1589785 (CHEMBL3830337) Agonist activity at GPR120 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay
- ChEMBL_1617107 (CHEMBL3859176) Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay
- ChEMBL_1621032 (CHEMBL3863315) Antagonist activity at human CCR6 assessed as inhibition of CCL20/MIP-3alpha-induced calcium flux
- ChEMBL_1621033 (CHEMBL3863316) Antagonist activity at human histamine H4 receptor assessed as inhibition of histamine-induced calcium flux
- ChEMBL_1679911 (CHEMBL4030188) Positive allosteric modulation of rat M4 receptor assessed as increase in acetylcholine-induced calcium mobilization
- ChEMBL_1811113 (CHEMBL4310573) Negative allosteric modulation of human mGlu5 receptor assessed as inhibition of glutamate induced-calcium mobilization
- ChEMBL_1929130 (CHEMBL4432306) Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response
- ChEMBL_1929131 (CHEMBL4432307) Antagonist activity at human muscarinic M1 receptor assessed as inhibition of acetylcholine-induced calcium response
- ChEMBL_1929132 (CHEMBL4432308) Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium response
- ChEMBL_1929133 (CHEMBL4432309) Antagonist activity at human muscarinic M3 receptor assessed as inhibition of acetylcholine-induced calcium response
- ChEMBL_1929134 (CHEMBL4432310) Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium response
- ChEMBL_2118954 (CHEMBL4828020) Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assay
- ChEMBL_214406 (CHEMBL820271) Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor
- ChEMBL_214539 (CHEMBL819376) Inhibition of 1 nM AVP-induced calcium mobilisation in cells expressing human vasopressin V1a receptor
- ChEMBL_2160609 (CHEMBL5045359) Negative allosteric modulator activity at human recombinant mGlur2 expressed in HEK293 cells by calcium assay
- ChEMBL_2165223 (CHEMBL5050084) Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assay
- ChEMBL_2165224 (CHEMBL5050085) Agonist activity at human OX1R expressed in CHO-K1 cells by FLIPR calcium flux assay
- ChEMBL_2220274 (CHEMBL5133608) Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assay
- ChEMBL_2220275 (CHEMBL5133609) Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assay
- ChEMBL_2243620 (CHEMBL5157830) Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization
- ChEMBL_304392 (CHEMBL830042) Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells
- ChEMBL_310399 (CHEMBL833177) Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cells
- ChEMBL_326994 (CHEMBL863527) Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assay
- ChEMBL_326995 (CHEMBL865847) Inhibition of calcium influx evoked by capsaicin in rat TRPV1 expressing cells by fluorescence assay
- ChEMBL_328833 (CHEMBL859852) Ability to inhibit domoic acid-induced increase of calcium in rat HEK293 cells expressing GluR5
- ChEMBL_333794 (CHEMBL864734) Inhibitory activity against L-type calcium channel in SD rat thoracic aorta by Magnus method
- ChEMBL_340096 (CHEMBL861246) Efficacy against human recombinant 5HT2B receptor induced intracellular calcium mobilization in CHO cells by FLIPR
- ChEMBL_340097 (CHEMBL861247) Efficacy against human recombinant 5HT2C receptor induced intracellular calcium mobilization in CHO cells by FLIPR
- ChEMBL_341803 (CHEMBL865005) Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assay
- ChEMBL_342816 (CHEMBL868829) Agonist activity on human recombinant TRPV1-mediated enhancement of intracellular calcium concentration in HEK293 cells
- ChEMBL_375693 (CHEMBL864920) Antagonist activity against CCR2 assessed as inhibition of MCP1-induced calcium flux in human monocytes
- ChEMBL_397503 (CHEMBL864285) Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPR
- ChEMBL_397504 (CHEMBL864286) Activity at human mGluR1 assessed as effect on glutamate-induced calcium ion mobilization by FLIPR
- ChEMBL_397647 (CHEMBL856303) Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assay
- ChEMBL_425214 (CHEMBL855160) Antagonistic activity at rat bradykinin B1 receptor assessed as effect on DAK-mediated calcium mobilization
- ChEMBL_42923 (CHEMBL654566) Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenate
- ChEMBL_42939 (CHEMBL654581) Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.
- ChEMBL_431992 (CHEMBL918776) Inhibition of T-type calcium channel Cav3.1 with alpha-1G subunit by patch clamp assay
- ChEMBL_432306 (CHEMBL915566) Inhibition of alpha-1G T-type calcium channel expressed in HEK293 cells by electrophysiological method
- ChEMBL_440954 (CHEMBL890045) Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilization
- ChEMBL_445299 (CHEMBL894439) Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization
- ChEMBL_445304 (CHEMBL894445) Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assay
- ChEMBL_44706 (CHEMBL656595) Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of rat brain
- ChEMBL_450371 (CHEMBL900656) Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilization
- ChEMBL_450372 (CHEMBL900655) Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilization
- ChEMBL_450373 (CHEMBL900657) Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization
- ChEMBL_453037 (CHEMBL902184) Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of calcium uptake
- ChEMBL_454874 (CHEMBL886904) Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells
- ChEMBL_456642 (CHEMBL922997) Antagonist activity at CCR2 receptor in PBMC assessed as inhibition of MCP1-induced calcium mobilization
- ChEMBL_458019 (CHEMBL924288) Activation of Drosophila melanogaster ryanodine receptor in Sf9 cells assessed as induction of calcium mobilization
- ChEMBL_460933 (CHEMBL944881) Activity at FFAR1 expressed in HEK-EM293 cells assessed as calcium influx by FLIPR assay
- ChEMBL_460936 (CHEMBL944884) Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium level
- ChEMBL_461493 (CHEMBL927504) Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilization
- ChEMBL_463344 (CHEMBL929487) Antagonist activity at human CCR2 in PBMCs assessed as inhibition of MCP1-induced calcium flux
- ChEMBL_463781 (CHEMBL932170) Agonist at human recombinant P2Y1 receptor expressed in human 1321 cells by calcium mobilization assay
- ChEMBL_464110 (CHEMBL949229) Antagonist activity at human CXCR3 expressed in CHO cells by FLIPR-based calcium mobilization assay
- ChEMBL_468549 (CHEMBL930973) Antagonist activity at rat muscarinic M1 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_468550 (CHEMBL930974) Antagonist activity at rat muscarinic M2 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_468551 (CHEMBL930975) Antagonist activity at rat muscarinic M3 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_468552 (CHEMBL930976) Antagonist activity at rat muscarinic M4 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_468553 (CHEMBL930977) Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells by calcium mobilization assay
- ChEMBL_512033 (CHEMBL970836) Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes
- ChEMBL_51504 (CHEMBL666022) Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)
- ChEMBL_556025 (CHEMBL964675) Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced calcium efflux
- ChEMBL_556955 (CHEMBL958141) Activity at CXCR4 in human CEM cells assessed as inhibition of CXCL12-induced calcium mobilization
- ChEMBL_571886 (CHEMBL1034756) Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization
- ChEMBL_572154 (CHEMBL1028510) Activation of ryanodine receptor 1 in mouse C2C12 cells assessed as induction of calcium mobilization
- ChEMBL_572155 (CHEMBL1028511) Activation of ryanodine receptor 2 in rat PC12 cells assessed as induction of calcium mobilization
- ChEMBL_592454 (CHEMBL1039645) Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay
- ChEMBL_598541 (CHEMBL1043533) Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR
- ChEMBL_626104 (CHEMBL1111630) Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilization
- ChEMBL_632325 (CHEMBL1112953) Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulation
- ChEMBL_632327 (CHEMBL1112955) Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulation
- ChEMBL_633008 (CHEMBL1118233) Antagonist activity at human TRPA1 channel assessed as inhibition of URB597-induced intracellular calcium influx
- ChEMBL_633009 (CHEMBL1118234) Antagonist activity at human TRPA1 channel assessed as inhibition of nifedipine-induced intracellular calcium influx
- ChEMBL_633015 (CHEMBL1118240) Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levels
- ChEMBL_633038 (CHEMBL1118738) Antagonist activity at human TRPA1 channel assessed as inhibition of formalin-induced intracellular calcium influx
- ChEMBL_652215 (CHEMBL1228488) Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization
- ChEMBL_652479 (CHEMBL1225682) Agonist activity at human 5HT2B receptor assessed as 10633-induced calcium mobilization by FLIPR assay
- ChEMBL_652481 (CHEMBL1225684) Agonist activity at human 5HT2C receptor assessed as 10633-induced calcium mobilization by FLIPR assay
- ChEMBL_695412 (CHEMBL1639082) Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization
- ChEMBL_718668 (CHEMBL1680819) Antagonist activity against human P2Y2 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assay
- ChEMBL_718669 (CHEMBL1680820) Antagonist activity against human P2Y4 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assay
- ChEMBL_718670 (CHEMBL1680821) Antagonist activity against human P2Y6 receptor expressed in 1321N1 astrocytoma cells by calcium mobilization assay
- ChEMBL_728638 (CHEMBL1685768) Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_728639 (CHEMBL1685769) Agonist activity at human S1P2 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_728640 (CHEMBL1685770) Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_728641 (CHEMBL1685771) Agonist activity at human S1P5 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_753427 (CHEMBL1799857) Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_753428 (CHEMBL1799858) Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels
- ChEMBL_802305 (CHEMBL1949463) Antagonist activity at human TRPA1 expressed in CHO cells assessed as inhibition of calcium influx
- ChEMBL_809691 (CHEMBL2016002) Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assay
- ChEMBL_818576 (CHEMBL2032863) Antagonist activity at rhesus monkey MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization
- ChEMBL_828579 (CHEMBL2060094) Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium mobilization
- ChEMBL_830694 (CHEMBL2061629) Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium mobilization
- ChEMBL_830695 (CHEMBL2061630) Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium mobilization
- ChEMBL_830696 (CHEMBL2061631) Antagonist activity at human muscarinic M3 receptor assessed as inhibition of acetylcholine-induced calcium mobilization
- ChEMBL_851680 (CHEMBL2155897) Agonist activity at human KISS1R assessed as induction of intracellular calcium mobilization by fluorometric analysis
- ChEMBL_851727 (CHEMBL2156069) Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization
- ChEMBL_852184 (CHEMBL2157605) Agonist activity at human OT7T175 assessed as increase in intracellular calcium level by FLIPR assay
- ChEMBL_92632 (CHEMBL699858) Inhibition of calcium release in Jurkat cells after T-cell receptor cross linking antibody treatment
- ChEMBL_92797 (CHEMBL703975) Calcium antagonistic activity by measuring [3H]nitrendipine displacement from rat heart L-type [Ca2+] channel
- ChEMBL_960591 (CHEMBL2389880) Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay
- ChEMBL_983856 (CHEMBL2433294) Positive modulation of human recombinant mGluR5 expressed in HEK293A cells by calcium based FLIPR assay
- ChEMBL_984153 (CHEMBL2432081) Agonist activity at PAR2 in human 16HBE14o- cells assessed as increase in intracellular calcium level