Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ec50 for monomerid = 356663
TargetCryptochrome-2(Homo sapiens)TBA
LigandPNGBDBM356663(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  194nMAssay Description:Modulation activity at CRY2/PER2 in human U2OS cells harboring per2-dLuc assessed as activation of per2 activity measured every 100 mins for 5 days b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356663(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  288nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356663(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  288nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent