Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 50006806
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration to inhibit Prostaglandin G/H synthase in the ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  9.10E+3nMAssay Description:Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed