Affinity DataIC50: 103nMAssay Description:Antagonist activity at MC4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of alpha-MSH-induced cAMP production by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Antagonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Antagonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 708nMAssay Description:Antagonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Antagonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+3nMAssay Description:Antagonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:Antagonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+3nMAssay Description:Antagonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.19E+3nMAssay Description:Antagonist activity at the mutant MC4R I125L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair