Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ic50 for monomerid = 50272192
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDC7-DBF4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  332nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50: >5.28E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed