Compile Data Set for Download or QSAR
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Found 4 of ki for monomerid = 232923
Target3-hydroxyacyl-CoA dehydrogenase type-2(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  5.50E+3nM ΔG°:  -30.0kJ/mole IC50:  1.96E+4nM Kd:  496nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  5.50E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxyacyl-CoA dehydrogenase type-2(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  9.66E+4nM ΔG°:  -22.9kJ/mole IC50:  3.41E+5nM Kd:  496nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  9.66E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent