Compile Data Set for Download or QSAR
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Found 47 Enz. Inhib. hit(s) with all data for entry = 50018408
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  1.70nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  2.60nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50499377(CHEMBL3735194)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608114(CHEMBL5290660)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608113(CHEMBL5267367)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608112(CHEMBL5283802)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608116(CHEMBL5269658)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608115(CHEMBL5288199)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517959(CHEMBL4536115)
Affinity DataIC50:  21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517974(CHEMBL4457733)
Affinity DataIC50:  21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517966(CHEMBL4587811)
Affinity DataIC50:  21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517960(CHEMBL4447225)
Affinity DataIC50:  21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517967(CHEMBL4443828)
Affinity DataIC50:  27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517962(CHEMBL4462318)
Affinity DataIC50:  27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50517958(CHEMBL4470236)
Affinity DataIC50:  27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608110(CHEMBL5273741)
Affinity DataIC50:  32nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608109(CHEMBL5274305)
Affinity DataIC50:  37nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608111(CHEMBL5269307)
Affinity DataIC50:  43nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608118(CHEMBL5287460)
Affinity DataIC50:  52nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))TBA
LigandPNGBDBM50608126(CHEMBL5283595)
Affinity DataIC50: <75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))TBA
LigandPNGBDBM50608127(CHEMBL5286891)
Affinity DataIC50: <75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))TBA
LigandPNGBDBM50608128(CHEMBL5290778)
Affinity DataIC50: <75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))TBA
LigandPNGBDBM50608129(CHEMBL5286403)
Affinity DataIC50: <75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50608117(CHEMBL5288269)
Affinity DataIC50:  77nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50570877(CHEMBL4848882)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50608130(CHEMBL5271772)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM50608122(CHEMBL5291477)
Affinity DataIC50:  150nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50010462(CHEBI:78825 | CHEMBL3264002 | US11147816, RO512676...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50608120(CHEMBL5286229)
Affinity DataIC50:  190nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608119(CHEMBL5278588)
Affinity DataIC50:  197nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50162147(1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50:  360nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  380nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  600nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608120(CHEMBL5286229)
Affinity DataIC50:  980nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50506691(CHEMBL4515319)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608108(CHEMBL5284920)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50506690(CHEMBL4541986)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human DOT1L (1 to 416 residues) expressed in Escherichia coli (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM50608121(CHEMBL5276080)
Affinity DataIC50:  1.93E+3nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50608107(CHEMBL5286675)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608125(CHEMBL5285843)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50300028(CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of human G9a expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608124(CHEMBL5284371)
Affinity DataIC50:  5.72E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50608123(CHEMBL5281928)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of human G9a expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed