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Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50378702'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  22nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed