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Found 6 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase' and Ligand = 'BDBM81424'
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  930nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assay in presence of 0.05% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Borrelia burgdorferi)
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  1.70E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Helicobacter pylori (strain G27))
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  5.40E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes)
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50:  4.90E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed