Found 8 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50101858' 
Affinity DataKi: 0.396nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to mouse EP4 receptor by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counterChecked by AuthorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at rat EP4 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.142nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptorMore data for this Ligand-Target Pair
