TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2B (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2B (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.97E+4nM ΔG°: -26.3kJ/moleT: 30°CAssay Description:Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7.13E+4nM ΔG°: -24.1kJ/moleT: 30°CAssay Description:Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of human CAMK2B using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of CAMK2b (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0950nMAssay Description:Inhibition of human CAMK2B using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of CAMK2BMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Cyclin E-cyclin-dependent kinase 2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of CaMK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of PKC-beta II mediated IL-8 release from HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CAMK2betaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CAMK2 using autocamtide-2 as substrate after 30 mins by PKLight assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of human CaMK2betaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CaMK2betaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CAMK2 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CAMK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CaMK2beta (1 to 315 residues) using calmodulin a substrate incubated for 40 mins in presence of [gamma-33ATP] by radi...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CaMK2beta (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CAMK2 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2beta using [KKALRRQETVDAL] as substrateMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of CAMK2 using autocamtide-2 as substrate after 30 mins by PKLight assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CAMK2betaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CaMK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair