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Found
113
with Last Name = 'yamanishi' and Initial = 'ss'
Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
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Affinity Data
Ki: 0.0700nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
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Affinity Data
Ki: 0.360nM
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 0.550nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
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Affinity Data
Ki: 0.620nM
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
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Affinity Data
Ki: 0.790nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
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Affinity Data
Ki: 0.850nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
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Affinity Data
Ki: 0.890nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 1.20nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 1.20nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
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Affinity Data
Ki: 1.62nM
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
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Affinity Data
Ki: 3.31nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: 3.39nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
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Affinity Data
Ki: 4.57nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 7.24nM
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3D Structure (crystal)
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
Copy SMILES
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Affinity Data
Ki: 7.76nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85232
(CAS_67249-51-8 | ICI 106270)
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Affinity Data
Ki: 7.94nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(Aminoclonidine, p | CAS_66711-21-5 | NSC_51763 | p...)
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Affinity Data
Ki: 7.94nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
Copy SMILES
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Affinity Data
Ki: 9.33nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
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Affinity Data
Ki: 9.77nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019729
((S)-5-(4,5-Dihydro-1H-imidazol-2-yl)-5,6,7,8-tetra...)
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Affinity Data
Ki: 9.77nM
More data for this Ligand-Target Pair
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Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
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Affinity Data
Ki: 11.5nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: 13.2nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85233
(CAS_81447-78-1 | Levlofexidine)
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Affinity Data
Ki: 14.4nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
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Affinity Data
Ki: 15.1nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 15.5nM
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3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
((4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro...)
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Affinity Data
Ki: 15.5nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
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Affinity Data
Ki: 17.0nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
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Affinity Data
Ki: 17.0nM
More data for this Ligand-Target Pair
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
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Affinity Data
Ki: 19.9nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
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Affinity Data
Ki: 20.4nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81984
(CAS_29110-47-2 | Guanfacine | NSC_3519)
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Affinity Data
Ki: 20.4nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
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Affinity Data
Ki: 20.9nM
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(Aminoclonidine, p | CAS_66711-21-5 | NSC_51763 | p...)
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Affinity Data
Ki: 21.4nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)
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Affinity Data
Ki: 21.9nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
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Affinity Data
Ki: 24.0nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
Copy SMILES
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(Aminoclonidine, p | CAS_66711-21-5 | NSC_51763 | p...)
Copy SMILES
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Affinity Data
Ki: 29.5nM
More data for this Ligand-Target Pair
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
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Affinity Data
Ki: 30.9nM
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
((4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro...)
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Affinity Data
Ki: 31.6nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
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Affinity Data
Ki: 33.1nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: 33.9nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 36.3nM
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
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Affinity Data
Ki: 37.1nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
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Affinity Data
Ki: 40.7nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)
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Affinity Data
Ki: 43.6nM
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PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
PDB
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ChEBI
CHEMBL
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PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
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Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85234
(CAS_81167-16-0 | IMILOXAN | NSC_133621)
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Affinity Data
Ki: 67.6nM
More data for this Ligand-Target Pair
Target Info
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