Compile Data Set for Download or QSAR
maximum 50k data
Found 193 of ic50 for UniProtKB: P10415
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562369((−)-4-chloro-14-cyclopropyl-7-{3-[(6-fluoro-...)
Affinity DataIC50:  1.20E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562386((+)-4-chloro-3,14-diethyl-7-{3-[(6-fluoronaphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577692(US11478451, Example 096 | US11478451, Example 097 ...)
Affinity DataIC50:  1.20E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562387((+)-4-chloro-3,14-diethyl-7-{3-[(6-fluoronaphthale...)
Affinity DataIC50:  1.30E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562382((rac)-4-chloro-14-cyclopropyl-3-ethyl-7-{3-[(6-flu...)
Affinity DataIC50:  1.40E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572202((rac)-4-chloro-12,12-difluoro-2,3-dimethyl-7-{3-[(...)
Affinity DataIC50:  1.40E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572166((rac)-4-chloro-3-ethyl-2-methyl-7-[3-(naphthalen-1...)
Affinity DataIC50:  1.40E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562391((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Affinity DataIC50:  1.40E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562385((rac)-4-chloro-3,14-diethyl-7-{3-[(6-fluoro-1-naph...)
Affinity DataIC50:  1.40E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562350((rac)-13-Chloro-12-ethyl-8,11-dimethyl-1-(3-((5,6,...)
Affinity DataIC50:  1.50E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572180((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Affinity DataIC50:  1.60E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562390((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Affinity DataIC50:  1.60E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577683(US11478451, Example 087 | US11478451, Example 088 ...)
Affinity DataIC50:  1.60E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562384((+)-4-chloro-14-cyclopropyl-3-ethyl-7-{3-[(6-fluor...)
Affinity DataIC50:  1.60E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562388((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoro-1-naphthyl)...)
Affinity DataIC50:  1.70E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562363((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Affinity DataIC50:  1.80E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562334((rac)-12-Ethyl-13-fluoro-1-(3-((6-fluoronaphthalen...)
Affinity DataIC50:  1.80E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577706((+)-4′-chloro-3′-ethyl-7′-{3-[(6...)
Affinity DataIC50:  1.80E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577698((rac)-3-chloro-4-ethyl-14-{3-[(6-fluoronaphthalen-...)
Affinity DataIC50:  1.80E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577689(US11478451, Example 093)
Affinity DataIC50:  1.80E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572157(4-chloro-3-ethyl-1-[2-(morpholin-4-yl)ethyl]-7-[3-...)
Affinity DataIC50:  1.90E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562392((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Affinity DataIC50:  1.90E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577717((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoro-1-naphthyl)...)
Affinity DataIC50:  1.90E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562368((rac)-4-chloro-14-cyclopropyl-7-{3-[(6-fluoro-1-na...)
Affinity DataIC50:  1.90E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572210((9aS,11 aR)-3-chloro-4,5-dimethyl-15-{3-[(naphthal...)
Affinity DataIC50:  1.90E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM577663((rac)-4-chloro-11,11,12,12-tetrafluoro-2,3-dimethy...)
Affinity DataIC50:  1.90E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM572192((rac)-4-chloro-3-ethyl-14-methyl-1-[2-(morpholin-4...)
Affinity DataIC50:  1.90E+4nMAssay Description:The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562256((rac)-2,3-Dimethyl-14-[2-(morpholin-4-yl)ethyl]-7-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562256((rac)-2,3-Dimethyl-14-[2-(morpholin-4-yl)ethyl]-7-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562256((rac)-2,3-Dimethyl-14-[2-(morpholin-4-yl)ethyl]-7-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562331((rac)-4-Chloro-2,3,14-trimethyl-7-{3-[(naphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562331((rac)-4-Chloro-2,3,14-trimethyl-7-{3-[(naphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562331((rac)-4-Chloro-2,3,14-trimethyl-7-{3-[(naphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562335((+)-3-Ethyl-4-fluoro-7-{3-[(6-fluoronaphthalen-1-y...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562336((−)-3-Ethyl-4-fluoro-7-{3-[(6-fluoronaphthal...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562338((+)-2,3,14-Trimethyl-7-[3-(1-naphthyloxy)propyl]-1...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562339((−)-2,3,14-Trimethyl-7-[3-(1-naphthyloxy)pro...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562340((rac)-12-Ethyl-11-methyl-1-(3-(naphthalen-1-yloxy)...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562341((rac)-12-Ethyl-11-methyl-1-(3-(naphthalen-1-yloxy)...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562342((rac)-12-Ethyl-11-methyl-8-(3-morpholinopropyl)-1-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562343((rac)-12-Ethyl-11-methyl-1-(3-(naphthalen-1-yloxy)...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562344((rac)-12-Ethyl-11-methyl-1-(3-(naphthalen-1-yloxy)...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562345(12-Ethyl-8,9,11-trimethyl-1-(3-(naphthalen-1-yloxy...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562346((rac)-13-Chloro-12-ethyl-1-(3-((6-fluoronaphthalen...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562347((rac)-13-Chloro-12-ethyl-8,11-dimethyl-1-(3-(napht...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562348((rac)-13-Chloro-1-(3-((2,3-dihydro-1H-inden-4-yl)o...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562349((rac)-13-Chloro-1-(3-(4-chloro-3,5-dimethylphenoxy...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562351((rac)-13-Chloro-12-ethyl-1-(34(4-fluoronaphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562352((rac)-13-Fluoro-1-(3-((6-fluoronaphthalen-1-yl)oxy...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM562353((rac)-13-Fluoro-8,11,12-trimethyl-1-(3-(naphthalen...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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