Compile Data Set for Download or QSAR
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Found 58 of ic50 for UniProtKB: P01857
LigandPNGBDBM507127(US11046675, Example 1006)
Affinity DataIC50:  2nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
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LigandPNGBDBM581058(US11492375, Example 1120)
Affinity DataIC50:  4nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM507051(US11046675, Example 1001)
Affinity DataIC50:  8.5nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
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LigandPNGBDBM581053(US11492375, Example 1115)
Affinity DataIC50:  11nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM507128(US11046675, Example 1007)
Affinity DataIC50:  33nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
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LigandPNGBDBM412139(US10392405, Compound Id 1.003 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412140(US10392405, Compound Id 1.004 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM581040(US11492375, Example 1102)
Affinity DataIC50: <100nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM412138(US10392405, Compound Id 1.002 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412137(US10392405, Compound Id 1.001 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM581043(US11492375, Example 1105)
Affinity DataIC50: <100nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581044(US11492375, Example 1106)
Affinity DataIC50: <100nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM412160(US10392405, Compound Id 1.024 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412158(US10392405, Compound Id 1.022 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412159(US10392405, Compound Id 1.023 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412157(US10392405, Compound Id 1.021 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412156(US10392405, Compound Id 1.020 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412155(US10392405, Compound Id 1.019 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412154(US10392405, Compound Id 1.018 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM581039(US11492375, Example 1101)
Affinity DataIC50: <100nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM412161(US10392405, Compound Id 1.025 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412150(US10392405, Compound Id 1.014 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412151(US10392405, Compound Id 1.015 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412152(US10392405, Compound Id 1.016 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
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LigandPNGBDBM412140(US10392405, Compound Id 1.004 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412147(US10392405, Compound Id 1.011 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412146(US10392405, Compound Id 1.010 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412148(US10392405, Compound Id 1.012 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412144(US10392405, Compound Id 1.008 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM412143(US10392405, Compound Id 1.007 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
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LigandPNGBDBM412142(US10392405, Compound Id 1.006 | US11059834, Compou...)
Affinity DataIC50:  300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
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LigandPNGBDBM507124(US11046675, Example 1003)
Affinity DataIC50:  775nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
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LigandPNGBDBM507123(US11046675, Example 1002)
Affinity DataIC50:  775nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM581031(US11492375, Example 1001)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581032(US11492375, Example 1002)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581059(US11492375, Example 1121)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581054(US11492375, Example 1116)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581048(US11492375, Example 1110)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581045(US11492375, Example 1107)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581042(US11492375, Example 1104)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581038(US11492375, Example 1100)
Affinity DataIC50:  1.05E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581041(US11492375, Example 1103)
Affinity DataIC50:  1.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581056(US11492375, Example 1118)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581060(US11492375, Example 1122)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581055(US11492375, Example 1117)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581051(US11492375, Example 1113 | US11492375, Example 111...)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581051(US11492375, Example 1113 | US11492375, Example 111...)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM581050(US11492375, Example 1112)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581046(US11492375, Example 1108)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
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LigandPNGBDBM581047(US11492375, Example 1109)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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