TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿A Di Perugia
Curated by ChEMBL
Universit¿A Di Perugia
Curated by ChEMBL
Affinity DataEC50: 6.60E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 1.09E+4nMAssay Description:Compound was tested for ability to stimulate metabotropic glutamate receptor (mGluR) mediated phosphoinositide hydrolysis in rat hippocampusMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1(Homo sapiens (Human))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataEC50: 6.50E+4nMAssay Description:Agonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slicesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...More data for this Ligand-Target Pair