Affinity DataIC50: 100nMAssay Description:Inhibitory activity against acetylcholinesterase in human RBCMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pre-incubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin) using butyrylthiocholine chloride as substrate incubated for 15 min prior to substrate addition ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition AChE (unknown origin) using ATCI as substrate assessed as hydrolysis of ATCI after 10 mins measured every 1 min for 10 timesMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Compound was assessed for in vitro inhibition of Acetylcholinesterase isolated from Electrophorus electricusMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibitory activity of the compound against acetylcholinesterase (AChE) from Torpedo californica (Reversible type of inhibition)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 400nMpH: 8.0 T: 2°CAssay Description:The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...More data for this Ligand-Target Pair
Affinity DataIC50: 418nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of electric eel AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 5 mins by DTNB-based s...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 15 min prior to substrate addition meas...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide as substrate preincubated for 15 minMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of AchE (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against AChE from electric eelMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:IC50 values for compounds 8, 15a, 15b, 16 and 17 determined with a microplate assay [Rhee et al., J. Chromatogr., 915:217-223] using lyophilised Elec...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataIC50: 538nMAssay Description:In vitro inhibitory effect on rat AcetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 540nMpH: 7.6 T: 2°CAssay Description:In a 96-well plate, 50 uL of the sample dissolved in phosphate buffer (8 mmol/L K2HPO4, 2.3 mmol/L NaH2PO4, 150 mmol/L NaCl, and 0.05% Tween 20 at pH...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of human AChE by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of electric eel AChE pretreated for 20 mins followed by acetylthiocholine iodide substrate addition measured for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured upto...More data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibition of human CholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of Torpedo californica AchE activity by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of AChE activityMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition by E...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate measured every 5 sec for 2 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 614nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 623nMAssay Description:Inhibition of electric eel AcetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zagreb
Curated by ChEMBL
University Of Zagreb
Curated by ChEMBL
Affinity DataIC50: 623nMAssay Description:Inhibition of electric eel AChE by Ellman's assayMore data for this Ligand-Target Pair