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Found 7 of ic50 for monomerid = 33601
TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  486nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  503nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  713nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed