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Found 5 Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM33601'
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  503nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed