Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 50146679
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146679((S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-...)
Affinity DataIC50:  7.90nMAssay Description:Antagonist activity towards human recombinant Endothelin A receptor expressed in chinese hamster ovary (CHO) cells determined using [125I]-ET-1 as ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146679((S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-...)
Affinity DataIC50:  89.8nMAssay Description:Antagonist activity towards human recombinant Endothelin B receptor expressed in chinese hamster ovary (CHO) cells determined using [125I]-ET-1 as ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146679((S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146679((S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146679((S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed