Compile Data Set for Download or QSAR
Found 1 of ic50 for monomerid = 50339746
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50339746(CHEMBL1689044 | rac-N-[1-Ethyl-1-(4-methylphenyl)p...)
Show SMILES CCC(CC)(NC(=O)c1c2NC(CC(C)(C)n2nc1-c1ccccc1)c1ccccc1)c1ccc(C)cc1
Show InChI InChI=1S/C33H38N4O/c1-6-33(7-2,26-20-18-23(3)19-21-26)35-31(38)28-29(25-16-12-9-13-17-25)36-37-30(28)34-27(22-32(37,4)5)24-14-10-8-11-15-24/h8-21,27,34H,6-7,22H2,1-5H3,(H,35,38)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding after 10 mins by scintillation countingMore data for this Ligand-Target Pair