BindingDB PrimarySearch

Found 16 of ic50 for monomerid = 50343148

TYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: 9.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPBMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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TYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: 1.15E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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TYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: 1.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Tyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human Lyp expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Tyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human FAP1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Tyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human LAR expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Receptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human PTPalpha expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Receptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human PTPB expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Dual specificity protein phosphatase 6(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human MKP3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Protein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human PRL1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Protein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Dual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Low molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Tyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human SHP2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Dual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)

IC50: >5.00E+4nMAssay Description:Inhibition of human VHR expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Filter my 16 hits

Targets 14▿
- TYR_PHOSPHATASE_2 domain-containing protein 3
- Receptor-type tyrosine-protein phosphatase beta 1
- Protein tyrosine phosphatase type IVA 3 1
- Tyrosine-protein phosphatase non-receptor type 13 1
- Tyrosine-protein phosphatase non-receptor type 22 1
- Tyrosine-protein phosphatase non-receptor type 11 1
- Protein tyrosine phosphatase type IVA 1 1
- Receptor-type tyrosine-protein phosphatase alpha 1
- Dual specificity protein phosphatase 3 1
- Dual specificity protein phosphatase 6 1
- Receptor-type tyrosine-protein phosphatase F 1
- Dual specificity protein phosphatase CDC14A 1
- Low molecular weight protein-tyrosine phosphatase A 1
- Tyrosine-protein phosphatase non-receptor type 9 1
Publications 1▿
- ACS Med Chem Lett 1: 355-359 (2010) 16
Institutions 1▿
- Indiana University School Of Medicine 16
Affinity: 9.1E+3 to 5.0E+4 nM▿
- IC50 16
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1