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Found 4 of ic50 for monomerid = 50398330
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant 6His-tagged USP7 using Ub-Rh110 as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  130nMAssay Description:Inhibition of human USP7 using ubiquitin-Rh110 as substrate incubated for 30 mins by Fluorometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed