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Found 2 Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50398330'
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed