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Found 7 of ic50 for monomerid = 50577302
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50:  32nMAssay Description:Inhibition of DNA-PK (unknown origin) using biotin-PEG2-TWSLPLSQDSASE-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50:  92nMAssay Description:Inhibition of DNA-PK in human HT-144 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50:  178nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PI(4,5)P2 as substrate incubated for 60 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50:  1.32E+3nMAssay Description:Displacement of 5-TAMRA-labelled Tracer A from human GST-fused/FLAG-tagged full length ATR/human N-terminal FLAG-tagged full length ATRIP expressed i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of mTOR (unknown origin) using biotin-Ahx-PPGDYSTTPGGTLFSTTPGGTRI-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1-antitrypsin-related protein(Homo sapiens)
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ATR in human HT29 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50577302(CHEMBL4860129)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of full-length N-terminal FLAG-tagged human ATM expressed in HEK293-6E cells using biotin-PEG2-SVEPPLSQETFSD as substrate preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed